ChemicalBook > CAS DataBase List > N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide

N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide

Product Name
N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide
CAS No.
1776112-90-3
Chemical Name
N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide
Synonyms
CPI-637;PF 6747775;PF-06747775;MAVELERTINIB;Mavelertinib( PF-06747775);N-[(3R,4R)-4-fluoro-1-[6-[(3-methoxy-1-methylpyrazol-4-yl)amino]-9-methylpurin-2-yl]pyrrolidin-3-yl]prop-2-enamide;N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide;2-Propenamide, N-[(3R,4R)-4-fluoro-1-[6-[(3-methoxy-1-methyl-1H-pyrazol-4-yl)amino]-9-methyl-9H-purin-2-yl]-3-pyrrolidinyl]-
CBNumber
CB13133470
Molecular Formula
C18H22FN9O2
Formula Weight
415.42
MOL File
1776112-90-3.mol
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N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide Property

Density 
1.52±0.1 g/cm3(Predicted)
storage temp. 
room temp
form 
powder
pka
12.93±0.40(Predicted)
color 
white to beige
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P314Get medical advice/attention if you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PZ0302
Product name
PF-06747775
Purity
≥98% (HPLC)
Packaging
5mg
Price
$47.2
Updated
2024/03/01
TRC
Product number
P218315
Product name
PF06747775
Packaging
0.5mg
Price
$160
Updated
2021/12/16
TRC
Product number
P218315
Product name
PF06747775
Packaging
10mg
Price
$2600
Updated
2021/12/16
TRC
Product number
P218315
Product name
PF06747775
Packaging
25mg
Price
$6275
Updated
2021/12/16
ChemScene
Product number
CS-0012907
Product name
Mavelertinib
Purity
≥99.0%
Packaging
1mg
Price
$200
Updated
2021/12/16
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N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide Chemical Properties,Usage,Production

Uses

PF 06747775 is an orally available inhibitor of the epidermall growth factor receptor (EGFR) mutant form T790M showing antineoplastic activity.

N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide Suppliers

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1776112-90-3, N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamideRelated Search:


  • MAVELERTINIB
  • N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide
  • PF-06747775
  • CPI-637
  • N-[(3R,4R)-4-fluoro-1-[6-[(3-methoxy-1-methylpyrazol-4-yl)amino]-9-methylpurin-2-yl]pyrrolidin-3-yl]prop-2-enamide
  • PF 6747775
  • 2-Propenamide, N-[(3R,4R)-4-fluoro-1-[6-[(3-methoxy-1-methyl-1H-pyrazol-4-yl)amino]-9-methyl-9H-purin-2-yl]-3-pyrrolidinyl]-
  • Mavelertinib( PF-06747775)
  • 1776112-90-3
  • C18H22FN9O2