9-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-9H-purin-6-amine

Product Name: 9-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-9H-purin-6-amine
CAS No.: 206055-70-1
Chemical Name: 9-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-9H-purin-6-amine
Synonyms: LNA-A;LNA-Adenosine;LNA Adenosine;2'-O-4'-C-Locked-A;2'-O-4'-C-Locked-rA;4'-C-Methyleneadenosine;2'-O-4'-C-locked-Adenosine;2'-O,4'-C-Methyleneadenosine;2’-O,4’-C-Methylene adenosine;2’-O,4’-C-Methyleneadenosine, LNA-A
CBNumber: CB13141035
Molecular Formula: C11H13N5O4
Formula Weight: 279.25
MOL File: 206055-70-1.mol

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9-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-9H-purin-6-amine Property

Boiling point:: 660.0±65.0 °C(Predicted)
Density: 2.14±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
pka: 12.98±0.60(Predicted)
form: Solid
color: White to off-white
InChI: InChI=1/C11H13N5O4/c12-8-5-9(14-3-13-8)16(4-15-5)10-6-7(18)11(1-17,20-10)2-19-6/h3-4,6-7,10,17-18H,1-2H2,(H2,12,13,14)/t6-,7+,10-,11+/s3
InChIKey: GHKDRNDFVCEETA-MIRGOXCMNA-N
SMILES: [C@@]12([H])[C@]([H])(O)[C@@](CO)(O[C@H]1N1C3=C(N=C1)C(N)=NC=N3)CO2 |&1:0,2,5,9,r|

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Hazard and Precautionary Statements (GHS)

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9-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-9H-purin-6-amine Chemical Properties,Usage,Production

Uses

2'-O,4'-C-Methyleneadenosine (LNA-A) is a locked nucleic acid (LNA) and is also an adenosine analog[1].

Biological Activity

2'-O,4'-C-Methyleneadenosine (LNA-A) is a locked nucleic acid (LNA) and is also an adenosine analog[1].

References

[1]. Ravn J, et al. Design, synthesis, and biological evaluation of LNA nucleosides as adenosine A3 receptor ligands. Bioorg Med Chem. 2007 Aug 15;15(16):5440-7.

9-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-9H-purin-6-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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9-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-9H-purin-6-amine Suppliers

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206055-70-1, 9-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-9H-purin-6-amineRelated Search:

1-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione 2'-O,4'-C-Methyleneguanosine 5-Methyl-2'-O,4'-C-methylenecytidine

9-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-9H-purin-6-amine

2'-O,4'-C-Methyleneadenosine

9H-Purin-6-amine, 9-[2,5-anhydro-4-C-(hydroxymethyl)-α-L-lyxofuranosyl]-

2’-O,4’-C-Methyleneadenosine, LNA-A

LNA-A

4'-C-Methyleneadenosine

LNA Adenosine

LNA-Adenosine

9-[2,5-Anhydro-4-C-(hydroxymethyl)-α-L-lyxofuranosyl]-9H-purin-6-amine

2'-O-4'-C-Locked-A

2'-O-4'-C-Locked-rA

2'-O-4'-C-locked-Adenosine

2’-O,4’-C-Methylene adenosine

1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)adenine

(1S,3R,4R,7S)-3-(6-Amino-9H-purin-9-yl)-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-7-ol

206055-70-1

Nucleosides

Nucleosides-LNA Nucleosides