ChemicalBook > CAS DataBase List > 9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 11,21-diacetate

9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 11,21-diacetate

Product Name
9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 11,21-diacetate
CAS No.
3949-26-6
Chemical Name
9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 11,21-diacetate
Synonyms
Dexamethasone Impurity 6;Dexamethasone Acetate Impurity I;Dexamethasone Acetate EP Impurity I;Dexamethasone Acetate Impurity 9(Dexamethasone Acetate EP Impurity I);9-fluoro-17-hydroxy-16α-methyl-3,20-dioxopregna-1,4-diene-11β,21-diyl diacetate;9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 11,21-diacetate;Pregna-1,4-diene-3,20-dione, 11,21-bis(acetyloxy)-9-fluoro-17-hydroxy-16-methyl-, (11β,16α)- (9CI);9-fluoro-17-hydroxy-16α-methyl-3,20-dioxopregna-1,4-diene-11β,21-diyl diacetate (dexamethasone 11,21-diacetate).;Dexamethasone impurity 9/Dexamethasone Acetate EP Impurity I/Dexamethasone 11,21-diacetate/9-fluoro-17-hydroxy-16α-methyl-3,20-dioxopregna- 1,4-diene-11β,21-diyl diacetate;2-((8S,9R,10S,11S,13S,14S,16R,17R)-11-acetoxy-9-fluoro-17-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
CBNumber
CB13141040
Molecular Formula
C26H33FO7
Formula Weight
476.53
MOL File
3949-26-6.mol
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9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 11,21-diacetate Property

Melting point:
257-264 °C
Boiling point:
583.4±50.0 °C(Predicted)
Density 
1.28±0.1 g/cm3(Predicted)
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
11.98±0.70(Predicted)
color 
Light Brown
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D298925
Product name
Dexamethasone11,21-diacetate
Packaging
50mg
Price
$160
Updated
2021/12/16
TRC
Product number
D298925
Product name
Dexamethasone11,21-diacetate
Packaging
250mg
Price
$675
Updated
2021/12/16
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9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 11,21-diacetate Chemical Properties,Usage,Production

Uses

Dexamethasone 11,21-diacetate, is an impuriy of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.

9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 11,21-diacetate Preparation Products And Raw materials

Raw materials

Preparation Products

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9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 11,21-diacetate Suppliers

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3949-26-6, 9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 11,21-diacetateRelated Search:


  • 2-((8S,9R,10S,11S,13S,14S,16R,17R)-11-acetoxy-9-fluoro-17-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
  • Dexamethasone Impurity 6
  • 9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 11,21-diacetate
  • Dexamethasone Acetate Impurity 9(Dexamethasone Acetate EP Impurity I)
  • Dexamethasone Acetate EP Impurity I
  • Dexamethasone Acetate Impurity I
  • Dexamethasone impurity 9/Dexamethasone Acetate EP Impurity I/Dexamethasone 11,21-diacetate/9-fluoro-17-hydroxy-16α-methyl-3,20-dioxopregna- 1,4-diene-11β,21-diyl diacetate
  • Pregna-1,4-diene-3,20-dione, 11,21-bis(acetyloxy)-9-fluoro-17-hydroxy-16-methyl-, (11β,16α)- (9CI)
  • 9-fluoro-17-hydroxy-16α-methyl-3,20-dioxopregna-1,4-diene-11β,21-diyl diacetate
  • 9-fluoro-17-hydroxy-16α-methyl-3,20-dioxopregna-1,4-diene-11β,21-diyl diacetate (dexamethasone 11,21-diacetate).
  • 2-((8S,9R,10S,11S,13S,14S,16R,17R)-11-Acetoxy-9-fluoro-17-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate (Dexamethasone Acetate Impurity)
  • 3949-26-6