N-(2-Phenoxyacetyl)guanosine
- Product Name
- N-(2-Phenoxyacetyl)guanosine
- CAS No.
- 119824-66-7
- Chemical Name
- N-(2-Phenoxyacetyl)guanosine
- Synonyms
- N2-PAC-rG;N2-Phenoxyacetylguanosine;N-(Phenoxyacetyl)guanosine;N-(2-Phenoxyacetyl)guanosine;Guanosine, N-(2-phenoxyacetyl)-;N-(9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-2-phenoxyacetamide
- CBNumber
- CB13141303
- Molecular Formula
- C18H19N5O7
- Formula Weight
- 417.37
- MOL File
- 119824-66-7.mol
N-(2-Phenoxyacetyl)guanosine Property
- Melting point:
- 159-160 °C
- Density
- 1.76±0.1 g/cm3(Predicted)
- pka
- 8.97±0.20(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 296396
- Product name
- N2-Phenoxyacetylguanosine
- Packaging
- 50g
- Price
- $516
- Updated
- 2021/12/16
- Product number
- NP45047
- Product name
- N2-Phenoxyacetylguanosine
- Packaging
- 10g
- Price
- $66
- Updated
- 2021/12/16
- Product number
- NP45047
- Product name
- N2-Phenoxyacetylguanosine
- Packaging
- 25g
- Price
- $135
- Updated
- 2021/12/16
- Product number
- NP45047
- Product name
- N2-Phenoxyacetylguanosine
- Packaging
- 50g
- Price
- $210
- Updated
- 2021/12/16
- Product number
- 6453EM
- Product name
- N-[9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-phenoxyacetamide
- Packaging
- 25g
- Price
- $232
- Updated
- 2021/12/16
N-(2-Phenoxyacetyl)guanosine Chemical Properties,Usage,Production
Uses
N2-Phenoxyacetylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
References
[1] Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51. DOI:10.1073/pnas.0631696100
N-(2-Phenoxyacetyl)guanosine Preparation Products And Raw materials
Raw materials
Preparation Products
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