FSL-1 lipoprotein, synthetic

Product Name: FSL-1 lipoprotein, synthetic
CAS No.: 322455-70-9
Chemical Name: FSL-1 lipoprotein, synthetic
Synonyms: (R)-FSL-1;FSL-1 ，S8428;FSL-1 >=80% (HPLC);FSL-1, TLR2/6 agonist;FSL-1 lipoprotein, synthetic;L-Phenylalanine, S-[2,3-bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-
CBNumber: CB13143802
Molecular Formula: C84H140N14O18S
Formula Weight: 1666.1584
MOL File: 322455-70-9.mol

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FSL-1 lipoprotein, synthetic Property

Boiling point:: 1659.8±65.0 °C(Predicted)
Density: 1?+-.0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: powder
pka: 3.46±0.10(Predicted)
color: Colorless
Water Solubility: H2O: soluble
Sequence: Ser-(2,3-Bispalmitoyloxypropyl)-Cys-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe

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Safety

WGK Germany: WGK 3
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1420
Product name: FSL-1
Purity: ≥80% (HPLC)
Packaging: 100 μg
Price: $293.28
Updated: 2025/07/31

Cayman Chemical

Product number: 24220
Product name: FSL-1
Purity: ≥95%
Packaging: 500μg
Price: $75
Updated: 2021/12/16

Cayman Chemical

Product number: 24220
Product name: FSL-1
Purity: ≥95%
Packaging: 1mg
Price: $143
Updated: 2021/12/16

Cayman Chemical

Product number: 24220
Product name: FSL-1
Purity: ≥95%
Packaging: 5mg
Price: $488
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0021000
Product name: (R,S)-PAM2CYS-GLY-ASP-PRO-LYS-HIS-PRO-LYS-SER-PHE-OH
Purity: 95.00%
Packaging: 5μG
Price: $598.26
Updated: 2021/12/16

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FSL-1 lipoprotein, synthetic Chemical Properties,Usage,Production

Uses

FSL-1, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to experimental HSV-2 infection[1][2].

Biological Activity

FSL-1 (Pam2CGDPKHPKSF) is a synthetic lipoprotein th at acts as a Toll-like Receptor 2/6 (TLR2/6) agonist and activator of nuclear transcription factor NF-KB. FSL-1 is based on the N-terminal part of the 44-kDa lipoprotein LP44 of Mycoplasma salivarium. FSL-1 showed higher stimulatory activity than MALP-2 in its ability to induce TNF-α production in macrophages and NF-KB in TLR2/TLR6 transfected HEK293 cells.', 'FSL-1 is a bacterial-derived toll-like receptor 2/6 agonist. It is capable of increasing resistance to herpes simplex virus type 2 (HSV-2) infection.

IC 50

TLR2; TLR6

storage

+4°C

References

[1] William A Rose 2nd, et al. FSL-1, a bacterial-derived toll-like receptor 2/6 agonist, enhances resistance to experimental HSV-2 infection. Virol J. 2009 Nov 10;6:195. DOI:10.1186/1743-422X-6-195
[2] Rasheed Ahmad, et al. FSL-1 induces MMP-9 production through TLR-2 and NF-κB /AP-1 signaling pathways in monocytic THP-1 cells. Cell Physiol Biochem. 2014;34(3):929-42. DOI:10.1159/000366310

FSL-1 lipoprotein, synthetic Preparation Products And Raw materials

Raw materials

Preparation Products

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FSL-1 lipoprotein, synthetic Suppliers

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322455-70-9, FSL-1 lipoprotein, syntheticRelated Search:

FSL-1 lipoprotein, synthetic

(R)-FSL-1

FSL-1 >=80% (HPLC)

L-Phenylalanine, S-[2,3-bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-

FSL-1, TLR2/6 agonist

FSL-1 ，S8428

322455-70-9