WSP-5
- Product Name
- WSP-5
- CAS No.
- 1593024-78-2
- Chemical Name
- WSP-5
- Synonyms
- WSP-5;Washington State Probe-5;DSMMZTASSIAQPQ-UHFFFAOYSA-N;3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2-(pyridin-2-yldisulfaneyl)benzoate);Benzoic acid, 2-(2-pyridinyldithio)-, 1,1'-(3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl) ester
- CBNumber
- CB13152767
- Molecular Formula
- C44H26N2O7S4
- Formula Weight
- 822.94
- MOL File
- 1593024-78-2.mol
WSP-5 Property
- Density
- 1.57±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C, protect from light
- solubility
- DMF: 30 mg/ml; DMSO: 25 mg/ml
- form
- A crystalline solid
- pka
- 1.69±0.19(Predicted)
- color
- White to off-white
- InChIKey
- DSMMZTASSIAQPQ-UHFFFAOYSA-N
- SMILES
- O=C1C2=CC=CC=C2C2(C3=CC=C(OC(C4C=CC=CC=4SSC4N=CC=CC=4)=O)C=C3OC3=CC(OC(C4C=CC=CC=4SSC4N=CC=CC=4)=O)=CC=C23)O1
N-Bromosuccinimide Price
- Product number
- 16929
- Product name
- WSP-5
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $35
- Updated
- 2024/03/01
- Product number
- 16929
- Product name
- WSP-5
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $105
- Updated
- 2024/03/01
- Product number
- 16929
- Product name
- WSP-5
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $193
- Updated
- 2024/03/01
- Product number
- 7564EH
- Product name
- [3-Oxo-6'-[2-(pyridin-2-yldisulfanyl)benzoyl]oxyspiro[2-benzofuran-1,9'-xanthene]-3'-yl]2-(pyridin-2-yldisulfanyl)benzoate
- Packaging
- 10mg
- Price
- $496
- Updated
- 2021/12/16
WSP-5 Chemical Properties,Usage,Production
Description
Hydrogen sulfide (H2S) is an important gaseous mediator, like nitric oxide, that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. WSP-5 is a turn-on fluorescent probe for hydrogen sulfide (H2S). Upon reaction with H2S, WSP-5 releases a fluorophore that displays excitation/emission maxima of 502/525 nm, respectively. WSP-5 exhibits a faster turn-on rate and a more sensitive detection limit toward H2S than WSP-1 .
Uses
WSP-5 is a fluorescent probe for fast detection of H2S in biological samples and cells. WSP-5 selectively and rapidly reacts with H2S and exhibits fluorescence through a reaction-based fluorescent turn-on strategy.
References
[1] BO PENG. Fluorescent Probes Based on Nucleophilic Substitution–Cyclization for Hydrogen Sulfide Detection and Bioimaging[J]. Chemistry - A European Journal, 2013, 20 4: 1010-1016. DOI: 10.1002/chem.201303757
[2] YINGZHU ZHOU. Sensitivity and Selectivity Analysis of Fluorescent Probes for Hydrogen Sulfide Detection[J]. Chemistry - An Asian Journal, 2022, 17 5. DOI: 10.1002/asia.202101399
[3] HALINA JURKOWSKA. New aspects of antiproliferative activity of 4-hydroxybenzyl isothiocyanate, a natural H2S-donor[J]. Amino Acids, 2018, 50 6: 699-709. DOI: 10.1007/s00726-018-2546-2
[4] CRISTIANE J. DA SILVA . NO, hydrogen sulfide does not come first during tomato response to high salinity[J]. Nitric oxide?: biology and chemistry, 2018, 76: Pages 164-173. DOI: 10.1016/j.niox.2017.09.008
WSP-5 Preparation Products And Raw materials
Raw materials
Preparation Products
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