Besifovir

Product Name: Besifovir
CAS No.: 1254032-66-0
Chemical Name: Besifovir
Synonyms: AR-11324;Netarsudil free base;Netarsudil，Besifovir;Netarsudil Impurity 8;(S)-4-(3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)benzyl 2,4-dimethylbenzoate;Benzoic acid, 2,4-dimethyl-, [4-[(1S)-1-(aminomethyl)-2-(6-isoquinolinylamino)-2-oxoethyl]phenyl]methyl ester
CBNumber: CB13159872
Molecular Formula: C28H27N3O3
Formula Weight: 453.53
MOL File: 1254032-66-0.mol

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Besifovir Property

Boiling point:: 711.9±60.0 °C(Predicted)
Density: 1.250±0.06 g/cm3(Predicted)
pka: 12.84±0.43(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

DC Chemicals

Product number: DC22821
Product name: Netarsudil
Purity: >98%
Packaging: 1g
Price: $1200
Updated: 2021/12/16

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Besifovir Chemical Properties,Usage,Production

Uses

Netarsudil is a Rho kinase (ROCK) and norepinephrine transporter (NET) inhibitor. Netarsudil increases outflow facility in human eyes through multiple mechanisms[1].

References

[1] Ren R, et al. Netarsudil Increases Outflow Facility in Human Eyes Through Multiple Mechanisms. Invest Ophthalmol Vis Sci. 2016 Nov 1;57(14):6197-6209. DOI:10.1167/iovs.16-20189

Besifovir Preparation Products And Raw materials

Raw materials

Preparation Products

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Besifovir Suppliers

China 26 India 4 United States 2 Global 32

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
Fax: 0755 28094224
Email: 3001272453@qq.com
Country: China
ProdList: 5158
Advantage: 50

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3506
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18333
Advantage: 56

Chengdu Miracle Pharmaceutical Co., Ltd.

Tel: 028-86136736 19130631884
Fax: 028-85265615
Email: sales@mic-pharma.com
Country: China
ProdList: 337
Advantage: 56

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shenzhen SUNGENING Bio-Medical Co., Ltd.

Tel: 0755-0755-28967200-8062 13631290199
Fax: 0755-28967200
Email: wxf@sungening.com
Country: China
ProdList: 9624
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Jiaxing Triview Biochemical Products Co., Ltd.

Tel: 0573-0573-87228088 17772796899
Fax: 0573-87228088
Email: triview@triviewbiochem.com
Country: China
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Shanghai Zhen Li Biological Technology Co., Ltd

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Fax: 13045646768
Email: zhenlipharma888@163.com
Country: China
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Jinan Yaoyan Pharmaceutical Co., Ltd.

Tel
Fax: -
Email: jnyaoyan@163.com
Country: China
ProdList: 3069
Advantage: 58

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19103
Advantage: 58

1254032-66-0, BesifovirRelated Search:

AR-11324

(S)-4-(3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)benzyl 2,4-dimethylbenzoate

Benzoic acid, 2,4-dimethyl-, [4-[(1S)-1-(aminomethyl)-2-(6-isoquinolinylamino)-2-oxoethyl]phenyl]methyl ester

Netarsudil Impurity 8

Netarsudil，Besifovir

Netarsudil free base

1254032-66-0