ChemicalBook > CAS DataBase List > EGF816 (S-enantiomer)
EGF816 (S-enantiomer)
- Product Name
- EGF816 (S-enantiomer)
- CAS No.
- 1508256-20-9
- Chemical Name
- EGF816 (S-enantiomer)
- Synonyms
- EGF816 (S-enantiomer);Nazartinib S-enantiomer (EGF816);N-[7-chloro-1-[(3S)-1-[(E)-4-(dimethylamino)but-2-enoyl]azepan-3-yl]benzimidazol-2-yl]-2-methylpyridine-4-carboxamide;4-Pyridinecarboxamide, N-[7-chloro-1-[(3S)-1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]hexahydro-1H-azepin-3-yl]-1H-benzimidazol-2-yl]-2-methyl-
- CBNumber
- CB13160069
- Molecular Formula
- C26H31ClN6O2
- Formula Weight
- 495.02
- MOL File
- 1508256-20-9.mol
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EGF816 (S-enantiomer) Property
- Density
- 1.28±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 50 mg/mL (101.01 mM); Water: < 0.1 mg/mL (insoluble)
- pka
- 11.38±0.43(Predicted)
- form
- Solid
- color
- White to off-white
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EGF816 (S-enantiomer) Chemical Properties,Usage,Production
Description
Nazartinib S-enantiomer (EGF816 S-enantiomer) is the less active S-enantiomer of Nazartinib. Nazartinib (EGF816) is an EGFR inhibitor.
References
[1]. Gerald Lelais, et al. Compounds and compositions for modulating egfr activity. WO 2013184757A1.
EGF816 (S-enantiomer) Preparation Products And Raw materials
Raw materials
Preparation Products
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EGF816 (S-enantiomer) Suppliers
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