NIH-12848

Product Name: NIH-12848
CAS No.: 959551-10-1
Chemical Name: NIH-12848
Synonyms: NIH-12848;NIH-12848, >98%;NIH12848;NIH 12848;NIH-12848, 959551-10-1;NIH-12848, 10 mM in DMSO;PI5P4Kγ Inhibitor, NIH-12848;PI5P4Kγ Inhibitor, NIH-12848;NIH-12848,NIH12848,Inhibitor,inhibit,NIH 12848;4-Quinazolinamine, N-(2-thienylmethyl)-2-[2-(trifluoromethyl)phenyl]-;N-(thiophen-2-ylmethyl)-2-(2-(trifluoromethyl)phenyl)quinazolin-4-amine
CBNumber: CB13161516
Molecular Formula: C20H14F3N3S
Formula Weight: 385.41
MOL File: 959551-10-1.mol

More

Less

NIH-12848 Property

Boiling point:: 441.6±45.0 °C(Predicted)
Density: 1.384±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 25 mg/mL
form: A crystalline solid
pka: 5.05±0.30(Predicted)
color: White to off-white
InChI: 1S/C20H14F3N3S/c21-20(22,23)16-9-3-1-7-14(16)19-25-17-10-4-2-8-15(17)18(26-19)24-12-13-6-5-11-27-13/h1-11H,12H2,(H,24,25,26)
InChIKey: QBDAEJRHUCSSPR-UHFFFAOYSA-N
SMILES: FC(F)(F)c1c(cccc1)c2nc3c(c(n2)NCc4[s]ccc4)cccc3

More

Less

Safety

WGK Germany: WGK 3
Storage Class: 11 - Combustible Solids

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 5.34333
Product name: PI5P4Kγ Inhibitor, NIH-12848
Packaging: 10 mg
Price: $166
Updated: 2026/03/19

Cayman Chemical

Product number: 26035
Product name: NIH 12848
Packaging: 5mg
Price: $116
Updated: 2024/03/01

Cayman Chemical

Product number: 26035
Product name: NIH 12848
Packaging: 25mg
Price: $353
Updated: 2024/03/01

Cayman Chemical

Product number: 26035
Product name: NIH 12848
Packaging: 1mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 26035
Product name: NIH 12848
Packaging: 10mg
Price: $161
Updated: 2024/03/01

More

Less

NIH-12848 Chemical Properties,Usage,Production

Uses

NIH-12848 is a a putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor, and also a potentially powerful tool for exploring the cell physiology of PI5P4Ks. Reagent in the synthesis and structure-activity relationship studies of N-benzyl-2-phenylpyrimidin-4-amines as potent USP1/UAF1 deubiquitinase inhibitors with anticancer activity against nonsmall cell lung cancer.

Biological Activity

Cell permeable: yes', 'Primary Target
PI5P4Kγ', 'Reversible: yes

NIH-12848 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

NIH-12848 Suppliers

China 64 United States 6 USA 1 Global 71

Shanghai JiYi Biotechnology Co. Ltd.

Tel: 13621943973
Fax: -
Email: sales@shjiyipharmatech.com
Country: China
ProdList: 1166
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 86249
Advantage: 60

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 7999
Advantage: 62

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 9550
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Medi-tech Bioscientific Co., Ltd.

Tel: 0519-83246372 13585352506
Fax: 0519-83246372
Country: China
ProdList: 1844
Advantage: 58

Twochem Co.Ltd.

Tel: 021-58111628 15800915896
Fax: QQ 3285589261
Email: sales@twochem.com
Country: China
ProdList: 1788
Advantage: 58

Angel Pharmatech, Ltd.

Tel: 17317130613
Fax: QQ3358272972
Email: 3358272972@qq.com
Country: China
ProdList: 3290
Advantage: 58

Tianjin Kaifu Pharmaceutical Technology Co., Ltd.

Tel: 18081075745
Email: chemflowtech@sina.com
Country: China
ProdList: 1886
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32467
Advantage: 58

959551-10-1, NIH-12848Related Search:

N-(thiophen-2-ylmethyl)-2-(2-(trifluoromethyl)phenyl)quinazolin-4-amine

NIH12848;NIH 12848

NIH-12848, >98%

NIH-12848

NIH-12848, 959551-10-1

4-Quinazolinamine, N-(2-thienylmethyl)-2-[2-(trifluoromethyl)phenyl]-

NIH-12848,NIH12848,Inhibitor,inhibit,NIH 12848

NIH-12848, 10 mM in DMSO

PI5P4Kγ Inhibitor, NIH-12848

959551-10-1

C20H14F3N3S