NH-(PEG3-t-butyl ester)2
- Product Name
- NH-(PEG3-t-butyl ester)2
- CAS No.
- 1814901-03-5
- Chemical Name
- NH-(PEG3-t-butyl ester)2
- Synonyms
- NH-(PEG3-CH2CH2COOtBu)2;HN-(PEG3-CH2CH2COOtBu)2;NH-(PEG3-t-butyl ester)2;NH-bis(PEG3-t-butyl ester);13-amino-bis(4,7,10-trioxadodecanoic acid tert-butyl ester);Di-tert-butyl 4,7,10,16,19,22-hexaoxa-13-azapentacosanedioate;Di-tert-butyl 4,7,10,16,19,22-Hexaoxa-13-azapentacosane-1,25-dioate;4,7,10,16,19,22-Hexaoxa-13-azapentacosanedioic acid, 1,25-bis(1,1-dimethylethyl) ester;HN-(PEG3-CH2CH2COOtBu)2/4,7,10,16,19,22-Hexaoxa-13-azapentacosanedioic acid, 1,25-bis(1,1-dimethylethyl) ester
- CBNumber
- CB13163080
- Molecular Formula
- C26H51NO10
- Formula Weight
- 537.68
- MOL File
- 1814901-03-5.mol
NH-(PEG3-t-butyl ester)2 Property
- Boiling point:
- 564.7±45.0 °C(Predicted)
- Density
- 1.050±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in Water, DMSO, DCM, DMF
- pka
- 8.39±0.19(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- BP-23234
- Product name
- NH-bis(PEG3-t-butylester)
- Purity
- 98%
- Packaging
- 250mg
- Price
- $280
- Updated
- 2021/12/16
- Product number
- BP-23234
- Product name
- NH-bis(PEG3-t-butylester)
- Purity
- 98%
- Packaging
- 500mg
- Price
- $430
- Updated
- 2021/12/16
- Product number
- BP-23234
- Product name
- NH-bis(PEG3-t-butylester)
- Purity
- 98%
- Packaging
- 1g
- Price
- $560
- Updated
- 2021/12/16
- Product number
- AS107847
- Product name
- HN-(PEG3-CH2CH2COOtBu)2
- Purity
- 97%
- Packaging
- 1g
- Price
- $790
- Updated
- 2021/12/16
- Product number
- B-1504
- Product name
- HN-(PEG3-CH2CH2COOtBu)2
- Purity
- 97%
- Packaging
- 1g
- Price
- $550
- Updated
- 2021/12/16
NH-(PEG3-t-butyl ester)2 Chemical Properties,Usage,Production
Description
NH-bis(PEG3-t-butyl ester) is a PEG linker containing an amino group and 3 PEG units. The amino groups is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
NH-bis(PEG3-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
NH-(PEG3-t-butyl ester)2 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from NH-(PEG3-t-butyl ester)2 manufacturers
- Product
- NH-bis(PEG3-t-butyl ester) 1814901-03-5
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >95.00%
- Supply Ability
- 1g
- Release date
- 2024-03-28