Prucalopride-13CD3
- Product Name
- Prucalopride-13CD3
- CAS No.
- 2140306-00-7
- Chemical Name
- Prucalopride-13CD3
- Synonyms
- Prucalopride-13CD3;4-amino-5-chloro-N-{1-[3-(13C,2H?)methoxypropyl]piperidin-4-yl}-2,3-dihydro-1-benzofuran-7-carboxamide
- CBNumber
- CB13163585
- Molecular Formula
- C18H23ClD3N3O3
- Formula Weight
- 371.88
- MOL File
- 2140306-00-7.mol
Prucalopride-13CD3 Property
- Density
- 1.286±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
- form
- Solid
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- 48435
- Product name
- Prucalopride-13CD3
- Packaging
- 1mg
- Price
- $650
- Updated
- 2021/12/16
Prucalopride-13CD3 Chemical Properties,Usage,Production
Uses
Prucalopride-13C,d3 is the 13C- and deuterium labeled Prucalopride[1].
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. DOI:10.1080/02688697.2018.1500521
[2] Briejer MR, et al. The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound. Eur J Pharmacol. 2001 Jun 29;423(1):71-83. DOI:10.1016/s0014-2999(01)01087-1
[3] Emmanuel AV, et al. Randomised clinical trial: the efficacy of prucalopride in patients with chronic intestinal pseudo-obstruction--a double-blind, placebo-controlled, cross-over, multiple n = 1 study. Aliment Pharmacol Ther. 2012 Jan;35(1):48-55. DOI:10.1111/j.1365-2036.2011.04907.x
[4] Bouras EP, et al. Selective stimulation of colonic transit by the benzofuran 5HT4 agonist, prucalopride, in healthy humans. Gut. 1999 May;44(5):682-6. DOI:10.1136/gut.44.5.682
Prucalopride-13CD3 Preparation Products And Raw materials
Raw materials
Preparation Products
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