CXCR2-IN-1
- Product Name
- CXCR2-IN-1
- CAS No.
- 1873376-49-8
- Chemical Name
- CXCR2-IN-1
- Synonyms
- CXCR2-IN-1;CXCR2 inhibitor 1;CXCR2-IN-1, 10 mM in DMSO;CXCR-2-IN-1,CXCR2 IN 1,CXCR2IN1;N-(2-Chloro-3-fluorophenyl)-N'-[4-chloro-2-hydroxy-3-[(1-methyl-4-piperidinyl)sulfonyl]phenyl]urea;Urea, N-(2-chloro-3-fluorophenyl)-N'-[4-chloro-2-hydroxy-3-[(1-methyl-4-piperidinyl)sulfonyl]phenyl]-
- CBNumber
- CB13171690
- Molecular Formula
- C19H20Cl2FN3O4S
- Formula Weight
- 476.35
- MOL File
- 1873376-49-8.mol
CXCR2-IN-1 Property
- Boiling point:
- 538.1±50.0 °C(Predicted)
- Density
- 1.528±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 5.4 mg/mL (11.34 mM)
- form
- Solid
- pka
- 5.02±0.10(Predicted)
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C585180
- Product name
- N-(2-Chloro-3-fluorophenyl)-N''-[4-chloro-2-hydroxy-3-[(1-methyl-4-piperidinyl)sulfonyl]phenyl]urea
- Packaging
- 2.5mg
- Price
- $715
- Updated
- 2021/12/16
- Product number
- CS-6467
- Product name
- CXCR2-IN-1
- Purity
- 99.26%
- Packaging
- 25mg
- Price
- $1000
- Updated
- 2021/12/16
- Product number
- CS-6467
- Product name
- CXCR2-IN-1
- Purity
- 99.26%
- Packaging
- 1mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- CS-6467
- Product name
- CXCR2-IN-1
- Purity
- 99.26%
- Packaging
- 5mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- CS-6467
- Product name
- CXCR2-IN-1
- Purity
- 99.26%
- Packaging
- 10mg
- Price
- $500
- Updated
- 2021/12/16
CXCR2-IN-1 Chemical Properties,Usage,Production
Uses
N-(2-Chloro-3-fluorophenyl)-N''-[4-chloro-2-hydroxy-3-[(1-methyl-4-piperidinyl)sulfonyl]phenyl]urea is a CNS penetrant CXCR2 antagonist.
in vivo
CXCR2-IN-1 shows efficacy in a cuprizone-induced demyelination model through oral administration, providing evidence to support CXCR2 to be a potential therapeutic target to treat demyelinating diseases such as multiple sclerosis[1].
IC 50
CXCR2: 9.3 (pIC50)
CXCR2-IN-1 Preparation Products And Raw materials
Raw materials
Preparation Products
CXCR2-IN-1 Suppliers
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
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- Country
- China
- ProdList
- 89689
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- +1-781-999-5354; +17819995354
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- United States
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- +1-708-310-1919 +1-13798911105
- Fax
- 708-557-7486
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- United States
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- 86-571-88216897,88216896 13588875226
- Fax
- 86-571-88216895
- sales@hzclap.com
- Country
- CHINA
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- 6312
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- Tel
- 18818260767
- Fax
- QQ 3610331285
- sales@chemegen.com
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- China
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- 88888888888
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- China
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- 13348960310 13348960310
- 3003867561@qq.com
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- China
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- 010-60605840 15801484223;
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- China
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- 13549236410
- sales@invivochem.cn
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- China
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- 4008200310
- marketing@tsbiochem.com
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- China
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