THEOPHYLLOL

Product Name: THEOPHYLLOL
CAS No.: 8002-89-9
Chemical Name: THEOPHYLLOL
Synonyms: THEOPHYLLOL;THEOPHENYLLOL;theocinsoluble;ionesodiumsalt;acet-theocinsodium;THEOPHYLLINE SODIUM ACETATE;theophyllinumnatriumaceticum;7-Theophyllineacetic acid sodium salt;theophylline,compd.withsodiumacetate(1:1);aceticacid,sodiumsalt,compd.withtheophylline(1:1)
CBNumber: CB1323470
Molecular Formula: C9H14N4Na2O4
Formula Weight: 288.21
MOL File: 8002-89-9.mol

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THEOPHYLLOL Property

form: powder to crystal
color: White to Almost white
CAS DataBase Reference: 8002-89-9

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Safety

RTECS: AJ4550000
HS Code: 2939.59.0000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: T0180
Product name: Theophyllol
Packaging: 25g
Price: $80
Updated: 2025/07/31

TRC

Product number: T343873
Product name: Theophyllol
Packaging: 2.5g
Price: $75
Updated: 2021/12/16

Chem-Impex

Product number: 32535
Product name: Theophyllol,98%(HPLC)
Purity: 98%(HPLC)
Packaging: 25G
Price: $78.4
Updated: 2021/12/16

Chem-Impex

Product number: 32535
Product name: Theophyllol,98%(HPLC)
Purity: 98%(HPLC)
Packaging: 1G
Price: $14
Updated: 2021/12/16

Chem-Impex

Product number: 32535
Product name: Theophyllol,98%(HPLC)
Purity: 98%(HPLC)
Packaging: 5G
Price: $22.4
Updated: 2021/12/16

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THEOPHYLLOL Chemical Properties,Usage,Production

Uses

Theophylline (1,3-Dimethylxanthine) sodium acetate is a potent phosphodiesterase (PDE) inhibitor, adenosine receptor antagonist, and histone deacetylase (HDAC) activator. Theophylline (1,3-Dimethylxanthine) sodium acetate inhibits PDE3 activity to relax airway smooth muscle. Theophylline (1,3-Dimethylxanthine) sodium acetate has anti-inflammatory activity by increase IL-10 and inhibit NF-κB into the nucleus. Theophylline (1,3-Dimethylxanthine) sodium acetate induces apoptosis. Theophylline (1,3-Dimethylxanthine) sodium acetate can be used for asthma and chronic obstructive pulmonary disease (COPD) research[1][2][3][4][5].

in vivo

Theophylline (1,3-Dimethylxanthine) (100 mg/kg; i.p.; daily, for 9 d; male Swiss mice) has anti-inflammatory activity in mice and increases IL-6 and IL-10 levels and inhibits TNF-α and NO^[1].

Animal Model:	Male Swiss mice^[1]
Dosage:	100 mg/kg
Administration:	Intraperitoneal injection; daily, for 9 days
Result:	Increased IL-6 and IL-10 levels and inhibited TNF-α and NO.

IC 50

IL-10; IL-6; PDE3; Human Endogenous Metabolite

References

[1] Rabe KF, et, al. Theophylline and selective PDE inhibitors as bronchodilators and smooth muscle relaxants. Eur Respir J. 1995 Apr;8(4):637-42. PMID:7664866
[2] Chung IY, et, al. The downregulation of Bcl-2 expression is necessary for theophylline-induced apoptosis of eosinophil. Cell Immunol. 2000 Aug 1;203(2):95-102. DOI:10.1006/cimm.2000.1678
[3] Ichiyama T, et, al. Theophylline inhibits NF-kappa B activation and I kappa B alpha degradation in human pulmonary epithelial cells. Naunyn Schmiedebergs Arch Pharmacol. 2001 Dec;364(6):558-61. DOI:10.1007/s00210-001-0494-x
[4] Ito K, et, al, Adcock IM, Barnes PJ. A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8921-6. DOI:10.1073/pnas.132556899
[5] Barnes PJ. Theophylline. Am J Respir Crit Care Med. 2013 Oct 15;188(8):901-6. DOI:10.1164/rccm.201302-0388PP

THEOPHYLLOL Preparation Products And Raw materials

Raw materials

Preparation Products

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THEOPHYLLOL Suppliers

China 17 Germany 2 India 1 Japan 1 United Kingdom 2 United States 5 Global 28

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
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TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
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Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
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9ding chemical ( Shanghai) Limited

Tel: 021-021-52271985 17721149837
Fax: +86 (21) 52271987
Email: sales@9dingchem.com
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Aikon International Limited

Tel: 025-58851090 15955137747
Fax: (6)02557626880
Email: sales01@aikonchem.com
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Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
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8002-89-9, THEOPHYLLOLRelated Search:

THEOPHYLLOL IMIDAZOLE SODIUM DERIVATIVE THEOPHYLLINE SODIUM GLYCINATE

THEOPHYLLINE SODIUM ACETATE

THEOPHYLLOL

aceticacid,sodiumsalt,compd.withtheophylline(1:1)

7-Theophyllineacetic acid sodium salt

aceticacid,sodiumsalt,mixt.with3,7-dihydro-1,3-dimethyl-1h-purine-2,6-d

acet-theocinsodium

ionesodiumsalt

theocinsoluble

theophylline,compd.withsodiumacetate(1:1)

theophyllinumnatriumaceticum

THEOPHENYLLOL

8002-89-9

C7H7N4NaO2C2H3NaO2

C7H7N4NaO2C2H3O2Na

C9H10N4Na2O4