Maleimide-NH-PEG12-CH2CH2COOPFP Ester

Product Name: Maleimide-NH-PEG12-CH2CH2COOPFP Ester
CAS No.: 2136296-33-6
Chemical Name: Maleimide-NH-PEG12-CH2CH2COOPFP Ester
Synonyms: Mal-NH-PEG12-CH2CH2COOPFP ester;Maleimide-NH-PEG12-CH2CH2COOPFP Ester;4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxa-40-azatritetracontanoic acid, 43-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-41-oxo-, 2,3,4,5,6-pentafluorophenyl ester
CBNumber: CB13309446
Molecular Formula: C40H59F5N2O17
Formula Weight: 934.89
MOL File: 2136296-33-6.mol

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Maleimide-NH-PEG12-CH2CH2COOPFP Ester Property

Boiling point:: 872.2±65.0 °C(Predicted)
Density: 1.272±0.06 g/cm3(Predicted)
pka: 15.01±0.46(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

purepeg

Product number: 436312
Product name: Maleimide-NH-PEG12-CH2CH2COOPFPEster
Purity: min.95%
Packaging: 250mg
Price: $340
Updated: 2021/12/16

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Maleimide-NH-PEG12-CH2CH2COOPFP Ester Chemical Properties,Usage,Production

Biological Activity

Mal-NH-PEG12-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Maleimide-NH-PEG12-CH2CH2COOPFP Ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Maleimide-NH-PEG12-CH2CH2COOPFP Ester Suppliers

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2136296-33-6, Maleimide-NH-PEG12-CH2CH2COOPFP EsterRelated Search:

Maleimide-NH-PEG12-CH2CH2COOPFP Ester

Mal-NH-PEG12-CH2CH2COOPFP ester

4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxa-40-azatritetracontanoic acid, 43-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-41-oxo-, 2,3,4,5,6-pentafluorophenyl ester

2136296-33-6