Maleimide-NH-PEG6-CH2CH2COOPFP Ester

Product Name: Maleimide-NH-PEG6-CH2CH2COOPFP Ester
CAS No.: 1599432-34-4
Chemical Name: Maleimide-NH-PEG6-CH2CH2COOPFP Ester
Synonyms: Mal-amido-PEG6-PFP Ester;Mal-NH-PEG6-CH2CH2COOPFP ester;Maleimide-NH-PEG6-CH2CH2COOPFP Ester;4,7,10,13,16,19-Hexaoxa-22-azapentacosanoic acid, 25-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-23-oxo-, 2,3,4,5,6-pentafluorophenyl ester
CBNumber: CB13309451
Molecular Formula: C28H35F5N2O11
Formula Weight: 670.58
MOL File: 1599432-34-4.mol

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Maleimide-NH-PEG6-CH2CH2COOPFP Ester Property

Boiling point:: 736.0±60.0 °C(Predicted)
Density: 1.345±0.06 g/cm3(Predicted)
pka: 15.01±0.46(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

purepeg

Product number: 436306
Product name: Maleimide-NH-PEG6-CH2CH2COOPFPEster
Purity: min.97%
Packaging: 1g
Price: $600
Updated: 2021/12/16

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Maleimide-NH-PEG6-CH2CH2COOPFP Ester Chemical Properties,Usage,Production

Biological Activity

Mal-NH-PEG6-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Maleimide-NH-PEG6-CH2CH2COOPFP Ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Maleimide-NH-PEG6-CH2CH2COOPFP Ester Suppliers

China 10 United States 3 Global 13

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1599432-34-4, Maleimide-NH-PEG6-CH2CH2COOPFP EsterRelated Search:

Maleimide-NH-PEG6-CH2CH2COOPFP Ester

Mal-NH-PEG6-CH2CH2COOPFP ester

4,7,10,13,16,19-Hexaoxa-22-azapentacosanoic acid, 25-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-23-oxo-, 2,3,4,5,6-pentafluorophenyl ester

Mal-amido-PEG6-PFP Ester

1599432-34-4