7-(tert-Butoxy)-7-oxoheptanoic acid
- Product Name
- 7-(tert-Butoxy)-7-oxoheptanoic acid
- CAS No.
- 1469894-57-2
- Chemical Name
- 7-(tert-Butoxy)-7-oxoheptanoic acid
- Synonyms
- 6-Boc-hexanoic Acid;7-(tert-Butoxy)-7-oxoheptanoic acid;Heptanedioic acid 1-tert-butyl ester;Heptanedioic acid, 1-(1,1-dimethylethyl) ester;7-[(2-methylpropan-2-yl)oxy]-7-oxoheptanoic acid;7-(tert-Butoxy)-7-oxoheptanoic acid/1469894-57-2/98%/1g
- CBNumber
- CB13334899
- Molecular Formula
- C11H20O4
- Formula Weight
- 216.27
- MOL File
- 1469894-57-2.mol
7-(tert-Butoxy)-7-oxoheptanoic acid Property
- Boiling point:
- 308.7±25.0 °C(Predicted)
- Density
- 1.038±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 4.74±0.10(Predicted)
- Appearance
- Colorless to light yellow Liquid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- 9688CZ
- Product name
- 7-(Tert-Butoxy)-7-oxoheptanoicacid
- Packaging
- 10g
- Price
- $1072
- Updated
- 2021/12/16
- Product number
- 9688CZ
- Product name
- 7-(Tert-Butoxy)-7-oxoheptanoicacid
- Packaging
- 25g
- Price
- $2220
- Updated
- 2021/12/16
- Product number
- CD61001541
- Product name
- 7-(tert-Butoxy)-7-oxoheptanoicacid
- Purity
- 98%
- Packaging
- 25g
- Price
- $1584
- Updated
- 2021/12/16
- Product number
- CD61001541
- Product name
- 7-(tert-Butoxy)-7-oxoheptanoicacid
- Purity
- 98%
- Packaging
- 250mg
- Price
- $35
- Updated
- 2021/12/16
- Product number
- CD61001541
- Product name
- 7-(tert-Butoxy)-7-oxoheptanoicacid
- Purity
- 98%
- Packaging
- 1g
- Price
- $99
- Updated
- 2021/12/16
7-(tert-Butoxy)-7-oxoheptanoic acid Chemical Properties,Usage,Production
Synthesis
111-16-0
75-65-0
1469894-57-2
The general procedure for the synthesis of 7-(tert-butoxy)-7-oxoheptanoic acid from heptanedioic acid and tert-butanol was as follows: heptanedioic acid (1.56 mL, 12.5 mmol), 2-methyl-2-propanol (14.9 mL, 156.3 mmol), EDCI (2.4 g, 12.5 mmol) and DMAP (1.53 g, 12.5 mmol) were dissolved in dichloromethane (15 mL). The reaction mixture was stirred at room temperature for 18 hours. After completion of the reaction, the reaction mixture was diluted with ether (60 mL) and washed sequentially with 0.01 N aqueous HCl and deionized water. The organic phase was dried with anhydrous magnesium sulfate and subsequently concentrated under reduced pressure to remove the solvent. The crude product was purified by column chromatography (eluent ratio 1:1 ethyl acetate:petroleum ether) to afford 7-(tert-butoxy)-7-oxoheptanoic acid (0.52 g, 2.42 mmol, 19% yield) as a colorless oil.1H NMR (400 MHz, DMSO-d6) δ ppm: 12.42 (br s, 1H), 2.18 (q, J = 7.4 Hz, 4H), 1.54-1.43 (m, 4H), 1.40 (s, 9H), 1.32-1.22 (m, 2H).
References
[1] Patent: WO2017/212329, 2017, A1. Location in patent: Page/Page column 29; 81
7-(tert-Butoxy)-7-oxoheptanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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