ChemicalBook > CAS DataBase List > H2N-PEG3-CH2COOtBu

H2N-PEG3-CH2COOtBu

Product Name
H2N-PEG3-CH2COOtBu
CAS No.
189808-70-6
Chemical Name
H2N-PEG3-CH2COOtBu
Synonyms
NH2-PEG3-C1-Boc;H2N-PEG3-CH2COOtBu;NH2-PEG3-CH2COOtBu;Amino-PEG3-CH2COOtBu;Amino-peg3-butyl ester;Amino-PEG3-CH2COOH t-Bu Ester;Amino-PEG3-CH2CO2-t-butyl ester;tert-Butyl 2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)acetate;Acetic acid, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester;H2N-PEG3-CH2COOtBu/Acetic acid, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
CBNumber
CB13340571
Molecular Formula
C12H25NO5
Formula Weight
263.33
MOL File
189808-70-6.mol
More
Less

H2N-PEG3-CH2COOtBu Property

Boiling point:
343.4±27.0 °C(Predicted)
Density 
1.041±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
Soluble in Water, DMSO, DCM, DMF
pka
8.74±0.10(Predicted)
form 
Liquid
color 
Colorless to light yellow
InChI
InChI=1S/C12H25NO5/c1-12(2,3)18-11(14)10-17-9-8-16-7-6-15-5-4-13/h4-10,13H2,1-3H3
InChIKey
OTTHWLFOQWLZKB-UHFFFAOYSA-N
SMILES
C(OC(C)(C)C)(=O)COCCOCCOCCN
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

BroadPharm
Product number
BP-23620
Product name
Amino-PEG3-CH2CO2-t-butylester
Purity
98%
Packaging
1g
Price
$215
Updated
2021/12/16
AK Scientific
Product number
AMTGC504
Product name
tert-Butyl 2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)acetate
Purity
97%
Packaging
1g
Price
$215
Updated
2021/12/16
Activate Scientific
Product number
AS104023
Product name
H2N-PEG3-CH2COOtBu
Purity
95+%
Packaging
1g
Price
$342
Updated
2021/12/16
Activate Scientific
Product number
AS104023
Product name
H2N-PEG3-CH2COOtBu
Purity
95+%
Packaging
5G
Price
$897
Updated
2021/12/16
purepeg
Product number
4328203
Product name
H2N-PEG3-CH2COOtBu
Purity
min.97%
Packaging
5G
Price
$650
Updated
2021/12/16
More
Less

H2N-PEG3-CH2COOtBu Chemical Properties,Usage,Production

Description

Amino-PEG3-CH2CO2-t-butyl ester is a PEG molecule containing an amino group with a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group (t-Boc) can be deprotected under acidic conditions.

Uses

NH2-PEG3-C1-Boc (PROTAC Linker 5) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005

H2N-PEG3-CH2COOtBu Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

H2N-PEG3-CH2COOtBu Suppliers

Canada 1 China 69 United States 5 Global 75
Shanghai Huici Pharmaceutical Technology Co., LTD
Tel
133-31922809 19372841038
Email
lixing@pharmahuici.com
Country
China
ProdList
732
Advantage
58
Chengdu Pukang Biotechnology Co., Ltd
Tel
+86-028-82550498 +86-19102685862
Fax
086-28-82550468
Email
sales@pu-kang.com
Country
China
ProdList
497
Advantage
58
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883
Fax
0731-82251112
Email
sales@huatengsci.com
Country
China
ProdList
5872
Advantage
58
Mashilabs (Shanghai) Co.,Ltd.
Tel
19916721580
Fax
QQ：3154870176
Email
mafarm@126.com
Country
China
ProdList
4542
Advantage
58
Borenpharm Co., Ltd
Tel
027-65563561
Fax
86-27-59218822
Email
sales@borenpharm.com
Country
China
ProdList
1245
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28785
Advantage
58
SHANGHAI FDC-CHEMICAL CO.,LTD
Tel
021-61469567 13482353728
Fax
021-61161605
Email
sales@fdc-chemical.com
Country
China
ProdList
9717
Advantage
58
Jiangsu aikang biomedical research and development co., LTD
Tel
025-58859352 13155353615
Email
qzhang@aikonchem.com
Country
China
ProdList
15525
Advantage
58
Jilin Province Woda Biotechnology Co., Ltd.
Tel
13504435624
Email
1927928688@qq.com
Country
China
ProdList
1615
Advantage
58
Wuhan Borenpharm Co., Ltd
Tel
027-65563561 18717150066
Fax
027-59218822
Email
3207347307@qq.com
Country
CHINA
ProdList
1238
Advantage
58
Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
Tel
13892832556
Email
2440688701@qq.com
Country
China
ProdList
1994
Advantage
58
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Email
sales@accelachem.com
Country
China
ProdList
10467
Advantage
58
Shaanxi borno biotechnology co., LTD
Tel
+86-13759708231
Email
asherw9@hotmail.com
Country
China
ProdList
2373
Advantage
58
Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD
Tel
025-86755008 17751752005
Fax
025-86755228
Email
hszhang@bestfluorodrug.com
Country
China
ProdList
2358
Advantage
58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49312
Advantage
58
Guangzhou Younan Technology Co., Ltd
Tel
020-82000279 18988941452
Fax
QQ：3283937693
Email
YN_research@163.com
Country
China
ProdList
3011
Advantage
58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tel
+86-021-61551413 +8618813727289
Email
contact@trustwe.com
Country
China
ProdList
5743
Advantage
58
Meng Cheng Technology (Shanghai) Co., LTD
Tel
400-820-6829
Email
sales@mitachieve.com
Country
China
ProdList
8860
Advantage
58
Zhengzhou Convergence Chemical Co. LTD
Tel
0371-0371-53736046 13393710386
Fax
QQ:2853979814
Email
2853979814@qq.com
Country
China
ProdList
9947
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Tel
021-51816796-820 13611835272
Fax
021-5161 3951
Email
sales2@sunwaypharm.com
Country
China
ProdList
44119
Advantage
58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
29668
Advantage
58
Zhengzhou Akem Chemical Co., Ltd
Tel
13303867194
Email
3001317055@qq.com
Country
China
ProdList
9681
Advantage
58
Nantong Hi-Future Biotechnology Co., Ltd
Tel
18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
2998
Advantage
58
Nanjing Yili Biotechnology Co., Ltd.
Tel
15380789538
Email
2885743537@qq.com
Country
China
ProdList
8205
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
40000
Advantage
58
JinOu Biomedical (Nanjing) Co., Ltd.
Tel
13000000000
Fax
jinoupharma@163
Email
jinoupharma@163.com
Country
China
ProdList
11721
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
59936
Advantage
58
Xi'an Qiyue Biotechnology Co., Ltd.
Tel
400-400-6966-012-012 17778955912
Email
2957605606@qq.com
Country
China
ProdList
2535
Advantage
58
Affinity（Wuhan）Ltd.
Tel
15841022315
Email
sales@affinitytech.cn
Country
China
ProdList
3000
Advantage
58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel
0431-80514535 19917294565
Email
et@chemextension.com
Country
China
ProdList
5061
Advantage
58
Pushan Industry (Shaanxi) Co., Ltd.
Tel
029-81310890 13571859809
Email
info@pushanshiye.com
Country
China
ProdList
9955
Advantage
58
Xianning Shen Lan Biomedical Research and Development Co., Ltd.
Tel
18171815831
Email
1341138380@qq.com
Country
China
ProdList
4310
Advantage
58
Aobolihui
Tel
0917-18691729 18691729963
Email
2553382659@qq.com
Country
China
ProdList
4739
Advantage
58
Nantong QuanYi Biotechnology Co., Ltd
Tel
0513-66337626 18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
5929
Advantage
58
Shanghai Easy CDMO Co.,Ltd
Tel
021-61734564 13854185395;
Email
info@easycdmo.com
Country
China
ProdList
10024
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 17801761073
Email
Gsiyu@solarbio.com
Country
China
ProdList
50464
Advantage
58
Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD
Tel
025-86755008 17751752005
Email
hszhang@bestfluorodrug.com
Country
China
ProdList
2820
Advantage
58
CHENGDU YINGNUOLING PHARMACEUTICAL TECHNOLOGY CO.,LTD
Tel
17882285575
Email
1276966012@qq.com
Country
China
ProdList
390
Advantage
58
Shandong Mingde Biotechnology Co., Ltd.
Tel
18560864701
Email
643971@qq.com
Country
China
ProdList
6098
Advantage
58
Shandong fen Boyu Biotechnology Co.,LTD
Tel
13356310019 13356310019;
Email
boyu2024@163.com
Country
China
ProdList
3247
Advantage
58
Chengdu Hanwei Biotechnology Co., Ltd
Tel
17360178904 18217049878
Email
zengzongwen@pegtide.com
Country
China
ProdList
1222
Advantage
58
Shanghai Zunlijia Life Technology Co., Ltd
Tel
021-34045219 13062664914
Email
huji@zunlijia.com
Country
China
ProdList
10027
Advantage
58
Jilin Chinese Academy of Sciences-yanshen Technology
Tel
18143011203
Email
ET-market@chemextension.com
Country
China
ProdList
32050
Advantage
58
Hubei wei shi reagent group ltd., company
Tel
027-59101766 13125137661
Email
2853877621@qq.com
Country
China
ProdList
7976
Advantage
58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
29423
Advantage
58
More
Less

View Lastest Price from H2N-PEG3-CH2COOtBu manufacturers

LAURENT
Product
NH2-PEG3-CH2COOtBu 189808-70-6
Price
US $69.00/g
Min. Order
10g
Purity
98%
Supply Ability
500kg
Release date
2025-11-17
R&D Scientific Inc.
Product
Amino-PEG3-CH2CO2-t-butyl ester 189808-70-6
Price
US $1500.00/g
Min. Order
1g
Purity
98
Supply Ability
5000 Kg
Release date
2025-05-07

189808-70-6, H2N-PEG3-CH2COOtBuRelated Search:

H2N-PEG2-CH2COOtBu 1-AMinooctaethylene Glycol TERT-BUTYL 12-AMINO-4 7 10-TRIOXA-DODECA 1,14-Diazido-3,6,9,12-tetraoxatetradecane 22-Amino-5,8,11,14,17,20-hexaoxa-2-azadocosanoic acid 1,1-dimethylethyl ester 2-[2-(2-Azidoethoxy)ethoxy]ethanamine alpha, oMega-DisucciniMidyl hexaethylene glycol 2-(2-Azidoethoxy)ethanol H2N-PEG11-CH2CH2COOH N3-PEG3-tBu Acid-PEG3-mono-methyl ester Amino-PEG10-alcohol Azide-PEG4-Tos alpha-aMine-oMega-propionic acid decaethylene glycol H2N-PEG12-tBu Azido-PEG7-azide Amino-PEG9-acid H2N-PEG24-CH2CH2COOtBu

  • H2N-PEG3-CH2COOtBu
  • Amino-PEG3-CH2CO2-t-butyl ester
  • tert-Butyl 2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)acetate
  • Amino-peg3-butyl ester
  • NH2-PEG3-C1-Boc
  • Acetic acid, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
  • NH2-PEG3-CH2COOtBu
  • Amino-PEG3-CH2COOtBu
  • Amino-PEG3-CH2COOH t-Bu Ester
  • H2N-PEG3-CH2COOtBu/Acetic acid, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
  • 189808-70-6
  • PROTAC LINKER
  • peg