ChemicalBook > CAS DataBase List > CPI-444
CPI-444
- Product Name
- CPI-444
- CAS No.
- 443103-97-7
- Chemical Name
- CPI-444
- Synonyms
- CPI-444 analog;A2AR antagonist 1;A2A receptor antagonist 1;A2A receptor antagonist 1, 10 mM in DMSO;1-(2-fluorobenzyl)-4-(furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine;1H-Pyrazolo[3,4-d]pyrimidin-6-amine, 1-[(2-fluorophenyl)methyl]-4-(2-furanyl)-;CPI444,CPI 444,Adenosine Receptor,disease,Parkinson,Inhibitor,CPI-444,hypolocomotion,inhibit,model,P1 receptor
- CBNumber
- CB13344887
- Molecular Formula
- C16H12FN5O
- Formula Weight
- 309.3
- MOL File
- 443103-97-7.mol
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CPI-444 Property
- Boiling point:
- 570.6±60.0 °C(Predicted)
- Density
- 1.49±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 62 mg/mL (200.45 mM)
- form
- Solid
- pka
- 3.17±0.10(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-6940
- Product name
- A2Areceptorantagonist1
- Purity
- 98.25%
- Packaging
- 1mg
- Price
- $80
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-6940
- Product name
- A2Areceptorantagonist1
- Purity
- 98.25%
- Packaging
- 5mg
- Price
- $120
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-6940
- Product name
- A2Areceptorantagonist1
- Purity
- 98.25%
- Packaging
- 10mg
- Price
- $190
- Updated
- 2021/12/16
AK Scientific
- Product number
- 2028AQ
- Product name
- 1-(2-fluorobenzyl)-4-(furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine
- Packaging
- 100mg
- Price
- $372.8
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- INB0005691
- Product name
- A2A RECEPTOR ANTAGONIST 1
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $458.04
- Updated
- 2021/12/16
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CPI-444 Chemical Properties,Usage,Production
Uses
A2A receptor antagonist 1 (CPI-444 analog) is an antagonist of both adenosine A2A receptor and A1 receptor with Ki values of 4 and 264 nM, respectively[1].
References
[1] Gillespie RJ, et al. Antagonists of the human adenosine A2A receptor. Part 3: Design and synthesis of pyrazolo[3,4-d]pyrimidines, pyrrolo[2,3-d]pyrimidines and 6-arylpurines. Bioorg Med Chem Lett. 2008 May 1;18(9):2924-9. DOI:10.1016/j.bmcl.2008.03.072
CPI-444 Preparation Products And Raw materials
Raw materials
Preparation Products
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