msx-130
- Product Name
- msx-130
- CAS No.
- 4051-59-6
- Chemical Name
- msx-130
- Synonyms
- msx-130;MSX-130 ,S0293;MSX-130; MSX 130; MSX130;1,4-bis(4,5-diphenyl-1H-imidazol-2-yl)benzene;1H-Imidazole, 2,2'-(1,4-phenylene)bis[4,5-diphenyl-;2-[4-(4,5-DIPHENYL-1H-IMIDAZOL-2-YL)PHENYL]-4,5-DIPHENYL-1H-IMIDAZOLE;CXCR4,MSX130,metastasis,Inhibitor,antagonist,CXC chemokine receptors,CXCR,MSX-130,cancer,inhibit
- CBNumber
- CB13350594
- Molecular Formula
- C36H26N4
- Formula Weight
- 514.62
- MOL File
- 4051-59-6.mol
msx-130 Property
- solubility
- DMSO:3.0(Max Conc. mg/mL);5.83(Max Conc. mM)
- form
- A solid
- color
- Light yellow to green yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CHM0309558
- Product name
- 2-[4-(4,5-DIPHENYL-1H-IMIDAZOL-2-YL)PHENYL]-4,5-DIPHENYL-1H-IMIDAZOLE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.63
- Updated
- 2021/12/16
- Product number
- CSN21269
- Product name
- MSX-130
- Packaging
- 25mg
- Price
- $526
- Updated
- 2021/12/16
- Product number
- DC11270
- Product name
- MSX-130
- Purity
- >98%
- Packaging
- 250mg
- Price
- $950
- Updated
- 2021/12/16
msx-130 Chemical Properties,Usage,Production
Uses
MSX-130 is a CXCR4 antagonist. MSX-130 inhibits cancer metastasis[1].
Biological Activity
MSX-130 is a CXCR4 antagonist. It inhibits tumor metastasis.
in vitro
The CXC chemokine receptor-4 (CXCR4) is a seven trans-membrane G-protein coupled receptor (GPCR) classified as a member of the family I GPCR or rhodopsin-like GPCR family. CXCR4 plays an important role in cancer metastasis, regulation of stem cell trafficking, and neovascularization.
target
| CXCR4
|
IC 50
CXCR4
References
[1] Zhan W, et al. Discovery of small molecule CXCR4 antagonists. J Med Chem. 2007 Nov 15;50(23):5655-64. DOI:10.1021/jm070679i
msx-130 Preparation Products And Raw materials
Raw materials
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View Lastest Price from msx-130 manufacturers
- Product
- msx-130 4051-59-6
- Price
- US $3.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200000KG
- Release date
- 2024-07-29
- Product
- msx-130 4051-59-6
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99。99%
- Supply Ability
- 200kg
- Release date
- 2019-12-24