ChemicalBook > CAS DataBase List > msx-130

msx-130

Product Name
msx-130
CAS No.
4051-59-6
Chemical Name
msx-130
Synonyms
msx-130;MSX-130 ,S0293;MSX-130; MSX 130; MSX130;1,4-bis(4,5-diphenyl-1H-imidazol-2-yl)benzene;1H-Imidazole, 2,2'-(1,4-phenylene)bis[4,5-diphenyl-;2-[4-(4,5-DIPHENYL-1H-IMIDAZOL-2-YL)PHENYL]-4,5-DIPHENYL-1H-IMIDAZOLE;CXCR4,MSX130,metastasis,Inhibitor,antagonist,CXC chemokine receptors,CXCR,MSX-130,cancer,inhibit
CBNumber
CB13350594
Molecular Formula
C36H26N4
Formula Weight
514.62
MOL File
4051-59-6.mol
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msx-130 Property

solubility 
DMSO:3.0(Max Conc. mg/mL);5.83(Max Conc. mM)
form 
A solid
color 
Light yellow to green yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM0309558
Product name
2-[4-(4,5-DIPHENYL-1H-IMIDAZOL-2-YL)PHENYL]-4,5-DIPHENYL-1H-IMIDAZOLE
Purity
95.00%
Packaging
5MG
Price
$502.63
Updated
2021/12/16
CSNpharm
Product number
CSN21269
Product name
MSX-130
Packaging
25mg
Price
$526
Updated
2021/12/16
DC Chemicals
Product number
DC11270
Product name
MSX-130
Purity
>98%
Packaging
250mg
Price
$950
Updated
2021/12/16
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msx-130 Chemical Properties,Usage,Production

Uses

MSX-130 is a CXCR4 antagonist. MSX-130 inhibits cancer metastasis[1].

Biological Activity

MSX-130 is a CXCR4 antagonist. It inhibits tumor metastasis.

in vitro

The CXC chemokine receptor-4 (CXCR4) is a seven trans-membrane G-protein coupled receptor (GPCR) classified as a member of the family I GPCR or rhodopsin-like GPCR family. CXCR4 plays an important role in cancer metastasis, regulation of stem cell trafficking, and neovascularization.

target

CXCR4

IC 50

CXCR4

References

[1] Zhan W, et al. Discovery of small molecule CXCR4 antagonists. J Med Chem. 2007 Nov 15;50(23):5655-64. DOI:10.1021/jm070679i

msx-130 Preparation Products And Raw materials

Raw materials

Preparation Products

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msx-130 Suppliers

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
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0431-0431-80514535 19917294565
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View Lastest Price from msx-130 manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
msx-130 4051-59-6
Price
US $3.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200000KG
Release date
2024-07-29
Career Henan Chemical Co
Product
msx-130 4051-59-6
Price
US $1.00/g
Min. Order
1g
Purity
99。99%
Supply Ability
200kg
Release date
2019-12-24

4051-59-6, msx-130Related Search:


  • msx-130
  • MSX-130; MSX 130; MSX130
  • 1H-Imidazole, 2,2'-(1,4-phenylene)bis[4,5-diphenyl-
  • 1,4-bis(4,5-diphenyl-1H-imidazol-2-yl)benzene
  • CXCR4,MSX130,metastasis,Inhibitor,antagonist,CXC chemokine receptors,CXCR,MSX-130,cancer,inhibit
  • 2-[4-(4,5-DIPHENYL-1H-IMIDAZOL-2-YL)PHENYL]-4,5-DIPHENYL-1H-IMIDAZOLE
  • MSX-130 ,S0293
  • 4051-59-6