Bendamustine Desmethyl Impurity

Product Name: Bendamustine Desmethyl Impurity
CAS No.: 41515-13-3
Chemical Name: Bendamustine Desmethyl Impurity
Synonyms: Bendamustine M4;BendamustineImpurity5-d4;N-desmethyl Bendamustine;4-(5-(bis(2-chloroethyl)amino)-1H;Bendamustine Impurity 5 (Desmethyl Impurity);N-Desmethylbendamustine trifluoroacetate salt;6-[bis(2-chloroethyl)amino]-1H-benzimidazole-2-butanoic acid;1H-Benzimidazole-2-butanoic acid, 6-[bis(2-chloroethyl)amino]-;Bendamustine impurity 10/Desmethyl Bendamustine/6-[Bis(2-chloroethyl)amino]-1H-Benzimidazole-2-butanoic Acid
CBNumber: CB13355908
Molecular Formula: C15H19Cl2N3O2
Formula Weight: 344.24
MOL File: 41515-13-3.mol

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Bendamustine Desmethyl Impurity Property

storage temp.: Store at -20°C
solubility: Acetonitrile:Methanol (1:1): soluble; DMSO: soluble
form: A solid

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 27171
Product name: N-desmethyl Bendamustine
Packaging: 1mg
Price: $383
Updated: 2024/03/01

Cayman Chemical

Product number: 27171
Product name: N-desmethyl Bendamustine
Packaging: 500μg
Price: $406
Updated: 2023/01/06

AK Scientific

Product number: 1877DC
Product name: N-Desmethylbendamustine
Packaging: 1mg
Price: $1011
Updated: 2021/12/16

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Bendamustine Desmethyl Impurity Chemical Properties,Usage,Production

Description

N-desmethyl Bendamustine is an active metabolite of the DNA alkylating agent bendamustine (Item No. 23693).1 N-desmethyl Bendamustine is formed through demethylation of the benzimidazole ring in bendamustine by the cytochrome P450 (CYP) isoform CYP1A2. It inhibits proliferation of non-cancerous peripheral blood leukocytes (PBLs; IC50 = 45 µM) and SU-DHL-1, SU-DHL-9, and Daudi lymphoma cells (IC50s = 270, 170, and 120 µM, respectively).WARNING This product is not for human or veterinary use.

Bendamustine Desmethyl Impurity Preparation Products And Raw materials

Raw materials

Preparation Products

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41515-13-3, Bendamustine Desmethyl ImpurityRelated Search:

Bendamustine Impurity 14 Bendamustine Impurity 8 Bendamustine Impurity D N1-Methylbenzene-1,2,4-triaMine GLUTARIC ACID-2-METHYLAMINO-5-NITROMONOANILIDE BendaMustine IMpurity C　　 5-[Bis(2-hydroxyethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid 5-[Bis(2-chloroethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid Methyl Ester Bendamustine Impurity 16 DesMethyl BendaMustine Hydrochloride 5-[(2-Chloroethyl)(2-hydroxyethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid Bendamustine Impurity 5 5-[Bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester Bendamustine Impurity 15 BendaMustine IMpurity A　　 5-[bis-(2-Chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester Bendamustine Ether Impurity 5-[(2-Chloroethyl)(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid 1-Methylethyl Ester

4-(5-(bis(2-chloroethyl)amino)-1H

N-desmethyl Bendamustine

Bendamustine impurity 10/Desmethyl Bendamustine/6-[Bis(2-chloroethyl)amino]-1H-Benzimidazole-2-butanoic Acid

N-Desmethylbendamustine trifluoroacetate salt

Bendamustine Impurity 5 (Desmethyl Impurity)

1H-Benzimidazole-2-butanoic acid, 6-[bis(2-chloroethyl)amino]-

Bendamustine M4

BendamustineImpurity5-d4

6-[bis(2-chloroethyl)amino]-1H-benzimidazole-2-butanoic acid

41515-13-3