Eniporide hydrochloride
- Product Name
- Eniporide hydrochloride
- CAS No.
- 211813-86-4
- Chemical Name
- Eniporide hydrochloride
- Synonyms
- Eniporide hydrochloride
- CBNumber
- CB13356152
- Molecular Formula
- C14H17ClN4O3S
- Formula Weight
- 356.83
- MOL File
- 211813-86-4.mol
Eniporide hydrochloride Property
- storage temp.
- Store at -20°C
- solubility
- DMSO: ≥ 150 mg/mL (420.37 mM)
- form
- Solid
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- CS-7831
- Product name
- Eniporidehydrochloride
- Purity
- 99.05%
- Packaging
- 5mg
- Price
- $84
- Updated
- 2021/12/16
- Product number
- CS-7831
- Product name
- Eniporidehydrochloride
- Purity
- 99.05%
- Packaging
- 10mg
- Price
- $144
- Updated
- 2021/12/16
- Product number
- CS-7831
- Product name
- Eniporidehydrochloride
- Purity
- 99.05%
- Packaging
- 25mg
- Price
- $288
- Updated
- 2021/12/16
- Product number
- CS-7831
- Product name
- Eniporidehydrochloride
- Purity
- 99.05%
- Packaging
- 50mg
- Price
- $504
- Updated
- 2021/12/16
Eniporide hydrochloride Chemical Properties,Usage,Production
Uses
Eniporide hydrochloride (EMD-96785 hydrochloride) is a potent Na+/H+ exchange inhibitor.
in vivo
In stage 1, the administration of 100 mg and 150 mg eniporide results in smaller infarct sizes, especially in the angioplasty group. In contrast, in stage 2 there is no difference in the enzymatic infarct size between the three groups. Overall there is no effect of eniporide on clinical outcome (death, cardiogenic shock, heart failure, life-threatening arrhythmias). However, there is a significant reduction of the incidence of heart failure in patients reperfused late (>4 h)[2].
References
[1] Klass O, et al. Effect of the Na+/H+ exchange inhibitor eniporide on cardiac performance and myocardial high energy phosphates in pigs subjected to cardioplegic arrest. Ann Thorac Surg. 2004 Feb;77(2):658-63. DOI:10.1016/S0003-4975(03)01604-7
[2] Zeymer U, et al. The Na(+)/H(+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial. J Am Coll Cardiol. 2001 Nov 15;38(6):1644-50. DOI:10.1016/s0735-1097(01)01608-4
Eniporide hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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