PD-1/PD-L1 Inhibitor 3

ChemicalBook > CAS DataBase List > PD-1/PD-L1 Inhibitor 3

Product Name: PD-1/PD-L1 Inhibitor 3
CAS No.: 1629654-95-0
Chemical Name: PD-1/PD-L1 Inhibitor 3
Synonyms: PD-1/PD-L1-IN 3;PD-1/PD-L1 Inhibitor 3;PD-1/PD-L1 Inhibitor 3 TFA;PD-1/PD-L1 Inhibitor 3 USP/EP/BP;Glycinamide, N-(2-mercaptoacetyl)-L-phenylalanyl-N-methyl-L-alanyl-L-asparaginyl-L-prolyl-L-histidyl-L-leucyl-N-methylglycyl-L-tryptophyl-L-seryl-L-tryptophyl-N-methyl-L-norleucyl-N-methyl-L-norleucyl-L-arginyl-L-cysteinyl-, cyclic (1→14)-thioether
CBNumber: CB13362748
Molecular Formula: C89H126N24O18S
Formula Weight: 1852.17
MOL File: 1629654-95-0.mol

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PD-1/PD-L1 Inhibitor 3 Property

Density: 1.42±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 13.14±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology

Product number: B6191
Product name: PD-1/PD-L1Inhibitor3
Packaging: 5mg
Price: $1047
Updated: 2021/12/16

DC Chemicals

Product number: DC44154
Product name: PD-1/PD-L1-IN3
Purity: >98%
Packaging: 25mg
Price: $750
Updated: 2021/12/16

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PD-1/PD-L1 Inhibitor 3 Chemical Properties,Usage,Production

Biological Activity

pd-1/pd-l1 inhibitor 3 is a pd-1/pd-l1 interaction inhibitor.the anti-pd-1 and anti-pd-l1 compounds have been found to show impressive antitumor effects in various malignancies, such as melanoma. the greatest clinical outcome in unselected patients has been observed in melanoma. the tumor expression of pd-l1 is suggested to be a suggestive, inadequate, and predictive of response to immune-checkpoint blockade.

in vitro

pd-1/pd-l1 inhibitor 3 has been identified to be a potent and selective small molecule inhibitor blocking the interaction of programmed cell death protein 1 (pd-1) with its ligand protein (pd-l1) and with cd80. pd-1/pd-l1 inhibitor 3 was also found to act as an immunomodulator. in addition, pd-1/pd-l1 inhibitor 3 was found to have highly efficacious binding to pd-l1 and promote the increased functional activities of t cells. therefore, pd-1/pd-l1 inhibitor 3 could be regarded as a promising therapeutic treatment of cancer and infectious diseases, such as hepatitis c [1].

target

Target	Value
PD-1/PD-L1 interaction (Cell-free assay )	5.6 nM

References

[1] miller michael matthew, et al. patent, pub. no.:wo/2014/151634

PD-1/PD-L1 Inhibitor 3 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from PD-1/PD-L1 Inhibitor 3 manufacturers

Henan Bao Enluo International TradeCo.，LTD

Product: PD-1/PD-L1 Inhibitor 3 1629654-95-0
Price: US $45.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20tons
Release date: 2023-05-18

Dideu Industries Group Limited

Product: PD-1/PD-L1 Inhibitor 3 1629654-95-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-08-17

1629654-95-0, PD-1/PD-L1 Inhibitor 3Related Search:

PD-1/PD-L1 Inhibitor 4 PALLADIUM ON STRONTIUM CARBONATE, REDUCED

PD-1/PD-L1 Inhibitor 3

Glycinamide, N-(2-mercaptoacetyl)-L-phenylalanyl-N-methyl-L-alanyl-L-asparaginyl-L-prolyl-L-histidyl-L-leucyl-N-methylglycyl-L-tryptophyl-L-seryl-L-tryptophyl-N-methyl-L-norleucyl-N-methyl-L-norleucyl-L-arginyl-L-cysteinyl-, cyclic (1→14)-thioether

PD-1/PD-L1 Inhibitor 3 USP/EP/BP

PD-1/PD-L1-IN 3

PD-1/PD-L1 Inhibitor 3 TFA

1629654-95-0

C89H126N24O18S