bis-PEG2-endo-BCN

Product Name: bis-PEG2-endo-BCN
CAS No.: 1476737-97-9
Chemical Name: bis-PEG2-endo-BCN
Synonyms: bis-PEG2-endo-BCN;endo-BCN-PEG2-endo-BCN;5,8-Dioxa-2,11-diazadodecanedioic acid, 1,12-bis[(1R,8S)-bicyclo[6.1.0]non-4-yn-9-ylmethyl] ester, rel-
CBNumber: CB13363886
Molecular Formula: C28H40N2O6
Formula Weight: 500.63
MOL File: 1476737-97-9.mol

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bis-PEG2-endo-BCN Property

Boiling point:: 668.3±45.0 °C(Predicted)
Density: 1.20±0.1 g/cm3(Predicted)
solubility: Soluble in DMSO, DCM, DMF
pka: 11.75±0.46(Predicted)
form: Oil
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23401
Product name: bis-PEG2-endo-BCN
Purity: 95%
Packaging: 50mg
Price: $430
Updated: 2021/12/16

BroadPharm

Product number: BP-23401
Product name: bis-PEG2-endo-BCN
Purity: 95%
Packaging: 100mg
Price: $680
Updated: 2021/12/16

BroadPharm

Product number: BP-23401
Product name: bis-PEG2-endo-BCN
Purity: 95%
Packaging: 250mg
Price: $1360
Updated: 2021/12/16

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bis-PEG2-endo-BCN Chemical Properties,Usage,Production

Description

bis-PEG2-endo-BCN is a click chemistry reagent, The BCN group enable copper free click chemitry with azide-tagged molecules.

Uses

bis-PEG2-endo-BCN is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. bis-PEG2-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

Cleavable Linker

References

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268

bis-PEG2-endo-BCN Preparation Products And Raw materials

Raw materials

Preparation Products

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bis-PEG2-endo-BCN Suppliers

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View Lastest Price from bis-PEG2-endo-BCN manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Bis-PEG2-endo-BCN 1476737-97-9
Price: US $0.00/mg
Min. Order: 25mg
Purity: >95.00%
Supply Ability: 100mg
Release date: 2024-03-20

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bis-PEG2-endo-BCN

5,8-Dioxa-2,11-diazadodecanedioic acid, 1,12-bis[(1R,8S)-bicyclo[6.1.0]non-4-yn-9-ylmethyl] ester, rel-

endo-BCN-PEG2-endo-BCN

1476737-97-9