AZD-1390

Product Name: AZD-1390
CAS No.: 2089288-03-7
Chemical Name: AZD-1390
Synonyms: CS-2816;AZD-1390;AZD-1390;AZD 1390;azd1390, 10 mM in DMSO;azd1390,ATM/ATR,azd-1390,ATM and RAD3 related,AZD 1390,inhibit,Inhibitor,Ataxia telangiectasia mutated;7-fluoro-1-isopropyl-3-methyl-8-(6-(3-(piperidin-1-yl)propoxy)pyridin-3-yl)-1H-imidazo[4,5-c]quinolin-2(3H)-one;7-fluoro-1-isopropyl-3-methyl-8-(6-(3-(piperidin-1-yl)propoxy)pyridin-3-yl)-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one;7-Fluoro-1,3-dihydro-3-methyl-1-(1-methylethyl)-8-[6-[3-(1-piperidinyl)propoxy]-3-pyridinyl]-2H-imidazo[4,5-c]quinolin-2-one;2H-Imidazo[4,5-c]quinolin-2-one, 7-fluoro-1,3-dihydro-3-methyl-1-(1-methylethyl)-8-[6-[3-(1-piperidinyl)propoxy]-3-pyridinyl]-
CBNumber: CB13364535
Molecular Formula: C27H32FN5O2
Formula Weight: 477.57
MOL File: 2089288-03-7.mol

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AZD-1390 Property

Boiling point:: 617.4±55.0 °C(Predicted)
Density: 1.224±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO:10.0(Max Conc. mg/mL);20.93(Max Conc. mM)
Ethanol:80.0(Max Conc. mg/mL);168.51(Max Conc. mM)
form: A solid
pka: 9.22±0.10(Predicted)
color: White to off-white
InChIKey: VQSZIPCGAGVRRP-UHFFFAOYSA-N
SMILES: N1C2C(=CC(C3=CC=C(OCCCN4CCCCC4)N=C3)=C(F)C=2)C2N(C(C)C)C(=O)N(C)C=2C=1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-8217
Product name: AZD1390
Purity: 99.97%
Packaging: 1mg
Price: $100
Updated: 2021/12/16

ChemScene

Product number: CS-8217
Product name: AZD1390
Purity: 99.97%
Packaging: 5mg
Price: $200
Updated: 2021/12/16

ChemScene

Product number: CS-8217
Product name: AZD1390
Purity: 99.97%
Packaging: 10mg
Price: $290
Updated: 2021/12/16

ChemScene

Product number: CS-8217
Product name: AZD1390
Purity: 99.97%
Packaging: 25mg
Price: $590
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573348
Product name: AZD1390
Purity: >98%
Packaging: 100mg
Price: $986
Updated: 2021/12/16

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AZD-1390 Chemical Properties,Usage,Production

Uses

AZD 1390 is a potent, highly selective, orally bioavailable, brain-penetrant ATM inhibitor.

in vivo

Median survival of mice treated with AZD1390 and radiation are significantly longer than untreated control mice (p=0.001). No overt signs of treatment toxicity are observed with small animal radiation research platform (SARRP) contrary to wholehead irradiated mice that seem to develop mucositis and difficulties drinking and eating at doses >10 Gy in combination with AZD1390^[2].

IC 50

ATM

AZD-1390 Preparation Products And Raw materials

Raw materials

Preparation Products

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AZD-1390 Suppliers

China 61 India 1 United States 7 Global 69

Hangzhou ChangCun Biotechnology Co., Ltd.

Tel: 0571-; 13567100326
Fax: QQ158848739
Email: 158848739@qq.com
Country: China
ProdList: 108
Advantage: 50

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 12952
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Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9510
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ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3506
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18333
Advantage: 56

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883
Fax: 0731-82251112
Email: sales@huatengsci.com
Country: China
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Shanghai XingMo Biotechnology Co., Ltd.

Tel: +86 13524779951; 13524779951
Fax: QQ: 2075692521
Email: 2075692521@qq.com
Country: China
ProdList: 310
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Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4757
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Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 18101056239
Email: 3193328036@qq.com
Country: China
ProdList: 29760
Advantage: 68

2089288-03-7, AZD-1390Related Search:

CS-2816

7-Fluoro-1,3-dihydro-3-methyl-1-(1-methylethyl)-8-[6-[3-(1-piperidinyl)propoxy]-3-pyridinyl]-2H-imidazo[4,5-c]quinolin-2-one

AZD-1390;AZD 1390

AZD-1390

2H-Imidazo[4,5-c]quinolin-2-one, 7-fluoro-1,3-dihydro-3-methyl-1-(1-methylethyl)-8-[6-[3-(1-piperidinyl)propoxy]-3-pyridinyl]-

7-fluoro-1-isopropyl-3-methyl-8-(6-(3-(piperidin-1-yl)propoxy)pyridin-3-yl)-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one

azd1390,ATM/ATR,azd-1390,ATM and RAD3 related,AZD 1390,inhibit,Inhibitor,Ataxia telangiectasia mutated

7-fluoro-1-isopropyl-3-methyl-8-(6-(3-(piperidin-1-yl)propoxy)pyridin-3-yl)-1H-imidazo[4,5-c]quinolin-2(3H)-one

azd1390, 10 mM in DMSO

2089288-03-7

C27H32FN5O2