ChemicalBook > CAS DataBase List > Azeliragon HCl
Azeliragon HCl
- Product Name
- Azeliragon HCl
- CAS No.
- 1284150-65-7
- Chemical Name
- Azeliragon HCl
- Synonyms
- TTP488 HCl;Azeliragon HCl;Azeliragon HCl (TTP488;Azeliragon hydrochloride;Azeliragon dihydrochloride
- CBNumber
- CB13373061
- Molecular Formula
- C32H39Cl2N3O2
- Formula Weight
- 568.58
- MOL File
- 1284150-65-7.mol
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N-Bromosuccinimide Price
TRC
- Product number
- B750065
- Product name
- 3-(4-(2-Butyl-1-(4-(4-chlorophenoxy)phenyl)-1H-imidazol-4-yl)phenoxy)-N,N-diethylpropan-1-amineHydrochloride
- Packaging
- 10mg
- Price
- $235
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DC32283
- Product name
- AzeliragonHCl
- Packaging
- 1g
- Price
- $2200
- Updated
- 2021/12/16
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Azeliragon HCl Chemical Properties,Usage,Production
Description
Azeliragon, also known as TTP488 and PF-04494700, is a potent and orally active RAGE inhibitor. RAGE (receptor for advanced glycation endproducts) is a pattern recognition receptor, which affects the movement of amyloid, an Alzheimer's-associated protein, into the brain. In preclinical studies, azeliragon decreased brain amyloid in mice and improved their performance on behavior tests. Azeliragon is a promising agent for for Alzheimer's disease and cerebral amyloid angiopathy.
Uses
3-(4-(2-Butyl-1-(4-(4-chlorophenoxy)phenyl)-1H-imidazol-4-yl)phenoxy)-N,N-diethylpropan-1-amine Hyrochloride acts as a reagent in the preparation of imidazoles for the treatment of RAGE-mediated diseases and pharmacokinetics.
Azeliragon HCl Preparation Products And Raw materials
Raw materials
Preparation Products
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