Recilisib sodium

Product Name: Recilisib sodium
CAS No.: 922139-31-9
Chemical Name: Recilisib sodium
Synonyms: Ex-Rad;ON 01210.Na;ON01210 sodium;ON-01210 sodium;Brand name: Ex-RAD;4-[(E)-2-[(4-chlorophenyl)methylsulfonyl]ethenyl]benzoate;4-I(E)-2-[(4-chlorophenyl)methanesulfonyl] ethenyl]benzoate sodium
CBNumber: CB13382335
Molecular Formula: C16H12ClNaO4S
Formula Weight: 360.78
MOL File: 922139-31-9.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0007751
Product name: EX-RAD
Purity: 95.00%
Packaging: 5MG
Price: $498.09
Updated: 2021/12/16

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Recilisib sodium Chemical Properties,Usage,Production

Uses

Recilisib sodium (ON 01210) is a radioprotectant, which can activate AKT, PI3K activities in cells[1].

in vivo

Recilisib sodium (500 mg/kg) significantly increases the rate of recovery and differentiation of primitive bone marrow myeloid progenitor cells in mice. Recilisib sodium in combination with radiation reduces CFU numbers in mice, but the Recilisib sodium-treated mice consistently retain a capability to form differentiated colonies. Recilisib sodium treated mice have a progenitor cell population that is never completely depleted by radiation exposure^[1].

References

[1] Kang AD, et al. ON01210.Na (Ex-RAD) mitigates radiation damage through activation of the AKT pathway. PLoS One. 2013;8(3):e58355. DOI:10.1371/journal.pone.0058355

Recilisib sodium Preparation Products And Raw materials

Raw materials

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Recilisib sodium Suppliers

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922139-31-9, Recilisib sodiumRelated Search:

Ex-Rad

4-[(E)-2-[(4-chlorophenyl)methylsulfonyl]ethenyl]benzoate

4-I(E)-2-[(4-chlorophenyl)methanesulfonyl] ethenyl]benzoate sodium

Brand name: Ex-RAD

ON 01210.Na

ON01210 sodium

ON-01210 sodium

922139-31-9

C16H12ClNaO4S