FK-448 Free base

Product Name: FK-448 Free base
CAS No.: 85858-76-0
Chemical Name: FK-448 Free base
Synonyms: FK-448 Free base;FK 448 Free base,FK448 Free base;1-Naphthalenecarboxylic acid, 1,2,3,4-tetrahydro-, 4-[[4-(1-methylethyl)-1-piperazinyl]carbonyl]phenyl ester
CBNumber: CB13384773
Molecular Formula: C25H30N2O3
Formula Weight: 406.52
MOL File: 85858-76-0.mol

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FK-448 Free base Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

CSNpharm

Product number: CSN22162
Product name: FK-448Freebase
Packaging: 10mg
Price: $1360
Updated: 2021/12/16

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FK-448 Free base Chemical Properties,Usage,Production

Uses

FK-448 Free base is an effective and specific inhibitor of chymotrypsin, with an IC50 of 720 nM.

in vivo

FK-448 (20 mg/kg, i.p.) results in a decrease in the blood glucose level, and inhibits the degradation of insulin by pancreatic enzymes in rats. FK-448 (20 mg/kg, p.o.) also decreases the blood glucose level, and increases plasma IRI level in dogs^[2].

References

[1] Fujii S, et al. New synthetic inhibitors of chymotrypsin. J Biochem. 1984 Feb;95(2):319-22. DOI:10.1093/oxfordjournals.jbchem.a134611
[2] Fujii S, et al. Promoting effect of the new chymotrypsin inhibitor FK-448 on the intestinal absorption of insulin in rats and dogs. J Pharm Pharmacol. 1985 Aug;37(8):545-9. DOI:10.1111/j.2042-7158.1985.tb03064.x

FK-448 Free base Preparation Products And Raw materials

Raw materials

Preparation Products

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FK-448 Free base Suppliers

China 8 United States 4 Global 12

Twochem Co.Ltd.

Tel: 021-58111628 15800915896
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Country: China
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Angel Pharmatech, Ltd.

Tel: 17317130613
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Email: 3358272972@qq.com
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Tianjin Kaifu Pharmaceutical Technology Co., Ltd.

Tel: 18081075745
Email: chemflowtech@sina.com
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TargetMol Chemicals Inc.

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Beijing Jin Ming Biotechnology Co., Ltd.

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Email: psaitong@jm-bio.com
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TargetMol Chemicals Inc.

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Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
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Biosynth Biological Technology (Suzhou) Co Ltd

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Adooq Bioscience LLC

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TargetMol Chemicals Inc.

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TargetMol Chemicals Inc.

Tel: +1-781-999-5354;
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Country: United States
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85858-76-0, FK-448 Free baseRelated Search:

FK-448 Free base

1-Naphthalenecarboxylic acid, 1,2,3,4-tetrahydro-, 4-[[4-(1-methylethyl)-1-piperazinyl]carbonyl]phenyl ester

FK 448 Free base,FK448 Free base

85858-76-0