ARS-1630

Product Name: ARS-1630
CAS No.: 1698055-86-5
Chemical Name: ARS-1630
Synonyms: CPD2016;ARS-1630;ARS-1630;ARS 1630;ARS1630;inhibit,Ras,ARS-1630,ARS1630,Inhibitor,ARS 1630;1-{4-[6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl]piperazin-1-yl}prop-2-en-1-one;(R)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one;2-Propen-1-one, 1-[4-[(7R)-6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-
CBNumber: CB13386449
Molecular Formula: C21H17ClF2N4O2
Formula Weight: 430.84
MOL File: 1698055-86-5.mol

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ARS-1630 Property

Boiling point:: 614.7±55.0 °C(Predicted)
Density: 1.434±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : ≥ 69 mg/mL (160.15 mM)
form: Solid
pka: 6.03±0.35(Predicted)
color: White to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0035117
Product name: ARS-1630
Purity: 98.01%
Packaging: 5mg
Price: $250
Updated: 2021/12/16

ChemScene

Product number: CS-0035117
Product name: ARS-1630
Purity: 98.01%
Packaging: 10mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0035117
Product name: ARS-1630
Purity: 98.01%
Packaging: 25mg
Price: $690
Updated: 2021/12/16

ChemScene

Product number: CS-0035117
Product name: ARS-1630
Purity: 98.01%
Packaging: 50mg
Price: $990
Updated: 2021/12/16

ChemScene

Product number: CS-0035117
Product name: ARS-1630
Purity: 98.01%
Packaging: 100mg
Price: $1300
Updated: 2021/12/16

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ARS-1630 Chemical Properties,Usage,Production

Definition

ChEBI: ARS-1620 is a qinazoline derivative carrying chloro and fluoro substituents at positions 6 and 8 respectively, a 2-fluoro-6-hydroxyphenyl group at position 7, and a 4-(prop-2-enoyl)piperazin-1-yl group at position 4. A potent, selective, and orally bioavailable covalent KRAS-G12C inhibitor, it inhibits the protein coding gene KRAS (Kirsten rat sarcoma virus) with high potency in cells and animals. It has a role as an inhibitor, an antiviral agent and an antineoplastic agent.

ARS-1630 Preparation Products And Raw materials

Raw materials

Preparation Products

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ARS-1630 Suppliers

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1698055-86-5, ARS-1630Related Search:

ARS-1630

CPD2016

ARS-1630;ARS 1630;ARS1630

(R)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one

2-Propen-1-one, 1-[4-[(7R)-6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-quinazolinyl]-1-piperazinyl]-

inhibit,Ras,ARS-1630,ARS1630,Inhibitor,ARS 1630

1-{4-[6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl]piperazin-1-yl}prop-2-en-1-one

1698055-86-5