E3 ligase Ligand-Linker Conjugates 7

Product Name: E3 ligase Ligand-Linker Conjugates 7
CAS No.: 2064292-52-8
Chemical Name: E3 ligase Ligand-Linker Conjugates 7
Synonyms: VH03-linker;VH 032 Linker 2;(S, R, S)-AHPC-PEG4-amine;(S,R,S)-AHPC-PEG4-NH2 HCl;VH032-PEG4-NH2 hydrochloride;VHL032-keto-PEG4-C2-amine HCl;E3 ligase Ligand-Linker Conjugates 7;VHL Ligand-Linker Conjugates 4 hydrochloride;(S,R,S)-AHPC-PEG4-NH2 hydrochloride (VHL Ligand-Linker Conjugates 4 hydrochloride;(2R,4S)-1-((R)-17-amino-2-(tert-butyl)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
CBNumber: CB13386474
Molecular Formula: C32H50ClN5O8S
Formula Weight: 700.29
MOL File: 2064292-52-8.mol

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E3 ligase Ligand-Linker Conjugates 7 Property

storage temp.: 2-8°C, sealed storage, away from moisture
solubility: DMF: 1.1 mg/ml; DMSO: 1.1 mg/ml; Ethanol: 0.7 mg/ml; PBS (pH 7.2): 5 mg/ml
form: A crystalline solid
color: White to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 26149
Product name: VH 032 Linker 2
Packaging: 5mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 26149
Product name: VH 032 Linker 2
Packaging: 10mg
Price: $107
Updated: 2024/03/01

Cayman Chemical

Product number: 26149
Product name: VH 032 Linker 2
Packaging: 25mg
Price: $198
Updated: 2024/03/01

Cayman Chemical

Product number: 26149
Product name: VH 032 Linker 2
Packaging: 50mg
Price: $437
Updated: 2024/03/01

AK Scientific

Product number: 2260EL
Product name: (S,R,S)-AHPC-PEG4-NH2 hydrochloride
Packaging: 5mg
Price: $160
Updated: 2021/12/16

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E3 ligase Ligand-Linker Conjugates 7 Chemical Properties,Usage,Production

Uses

(S,R,S)-AHPC-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.

IC 50

VHL

References

[1] Crew, Andrew P, et al. MDM2-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE. US20170008904A1.

E3 ligase Ligand-Linker Conjugates 7 Preparation Products And Raw materials

Raw materials

Preparation Products

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E3 ligase Ligand-Linker Conjugates 7 Suppliers

China 46 United Kingdom 1 United States 4 Global 51

Bide Pharmatech Ltd.

Tel: 400-400-164-7117 18317119277
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Sigma-Aldrich

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Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
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Jiaxing Deyi Chemical Co., Ltd.

Tel: 86-0573-85866609 13325730825
Fax: 0573-85866609
Email: 945717149@qq.com
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Aikon International Limited

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Fax: (6)02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15949
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Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4952
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Henan Alfachem Co.,Ltd.

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SuZhou Medinoah Co.,LTD.

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Fax: 0512-69561982
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Jilin Province Woda Biotechnology Co., Ltd.

Tel: 13504435624
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Henan Alfa Chemical Co., Ltd

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View Lastest Price from E3 ligase Ligand-Linker Conjugates 7 manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: (S,R,S)-AHPC-PEG4-NH2 hydrochloride 2064292-52-8
Price: US $0.00/mg
Min. Order: 250mg
Purity: >98.00%
Supply Ability: 250mg
Release date: 2024-04-01

2064292-52-8, E3 ligase Ligand-Linker Conjugates 7Related Search:

E3 ligase Ligand-Linker Conjugates 7

(2S,4R)-1-((S)-17-amino-2-(tert-butyl)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecan-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride

VH 032 Linker 2

VH032-PEG4-NH2 hydrochloride

VHL Ligand-Linker Conjugates 4 hydrochloride

VH03-linker

(S,R,S)-AHPC-PEG4-NH2 hydrochloride (VHL Ligand-Linker Conjugates 4 hydrochloride

(2S,4R)-1-((S)-17-amino-2-(tert-butyl)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride

(2R,4S)-1-((R)-17-amino-2-(tert-butyl)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride

(2S,4R)-1-[(2S)-2-[[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide

(S, R, S)-AHPC-PEG4-amine

VHL032-keto-PEG4-C2-amine HCl

(S,R,S)-AHPC-PEG4-NH2 HCl

2064292-52-8