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E3 ligase Ligand-Linker Conjugates 7

Product Name
E3 ligase Ligand-Linker Conjugates 7
CAS No.
2064292-52-8
Chemical Name
E3 ligase Ligand-Linker Conjugates 7
Synonyms
VH03-linker;VH 032 Linker 2;(S, R, S)-AHPC-PEG4-amine;(S,R,S)-AHPC-PEG4-NH2 HCl;VH032-PEG4-NH2 hydrochloride;VHL032-keto-PEG4-C2-amine HCl;E3 ligase Ligand-Linker Conjugates 7;VHL Ligand-Linker Conjugates 4 hydrochloride;(S,R,S)-AHPC-PEG4-NH2 hydrochloride (VHL Ligand-Linker Conjugates 4 hydrochloride;(2R,4S)-1-((R)-17-amino-2-(tert-butyl)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
CBNumber
CB13386474
Molecular Formula
C32H50ClN5O8S
Formula Weight
700.29
MOL File
2064292-52-8.mol
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E3 ligase Ligand-Linker Conjugates 7 Property

storage temp. 
2-8°C, sealed storage, away from moisture
solubility 
DMF: 1.1 mg/ml; DMSO: 1.1 mg/ml; Ethanol: 0.7 mg/ml; PBS (pH 7.2): 5 mg/ml
form 
A crystalline solid
color 
White to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
26149
Product name
VH 032 Linker 2
Packaging
5mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
26149
Product name
VH 032 Linker 2
Packaging
10mg
Price
$107
Updated
2024/03/01
Cayman Chemical
Product number
26149
Product name
VH 032 Linker 2
Packaging
25mg
Price
$198
Updated
2024/03/01
Cayman Chemical
Product number
26149
Product name
VH 032 Linker 2
Packaging
50mg
Price
$437
Updated
2024/03/01
AK Scientific
Product number
2260EL
Product name
(S,R,S)-AHPC-PEG4-NH2 hydrochloride
Packaging
5mg
Price
$160
Updated
2021/12/16
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E3 ligase Ligand-Linker Conjugates 7 Chemical Properties,Usage,Production

Uses

(S,R,S)-AHPC-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.

IC 50

VHL

References

[1] Crew, Andrew P, et al. MDM2-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE. US20170008904A1.

E3 ligase Ligand-Linker Conjugates 7 Preparation Products And Raw materials

Raw materials

Preparation Products

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E3 ligase Ligand-Linker Conjugates 7 Suppliers

Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Jiaxing Deyi Chemical Co., Ltd.
Tel
86-0573-85866609 13325730825
Fax
0573-85866609
Email
945717149@qq.com
Country
China
ProdList
8593
Advantage
58
Aikon International Limited
Tel
025-58851090 15955137747
Fax
(6)02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15949
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
Advantage
58
Henan Alfachem Co.,Ltd.
Tel
0371-55051623 18137891487
Fax
QQ:2853979817
Email
2853979817@qq.com
Country
China
ProdList
9999
Advantage
58
SuZhou Medinoah Co.,LTD.
Tel
0512-69561983 13914027025
Fax
0512-69561982
Email
zhang_q@medinoah.com
Country
China
ProdList
3811
Advantage
58
Jilin Province Woda Biotechnology Co., Ltd.
Tel
13504435624
Email
1927928688@qq.com
Country
China
ProdList
1615
Advantage
58
Henan Alfa Chemical Co., Ltd
Tel
+8615838112936
Email
alfa10@alfachem.cn
Country
China
ProdList
12921
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Shaanxi borno biotechnology co., LTD
Tel
+86-13759708231
Email
asherw9@hotmail.com
Country
China
ProdList
2373
Advantage
58
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View Lastest Price from E3 ligase Ligand-Linker Conjugates 7 manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
(S,R,S)-AHPC-PEG4-NH2 hydrochloride 2064292-52-8
Price
US $0.00/mg
Min. Order
250mg
Purity
>98.00%
Supply Ability
250mg
Release date
2024-04-01

2064292-52-8, E3 ligase Ligand-Linker Conjugates 7Related Search:


  • E3 ligase Ligand-Linker Conjugates 7
  • (2S,4R)-1-((S)-17-amino-2-(tert-butyl)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecan-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
  • VH 032 Linker 2
  • VH032-PEG4-NH2 hydrochloride
  • VHL Ligand-Linker Conjugates 4 hydrochloride
  • VH03-linker
  • (S,R,S)-AHPC-PEG4-NH2 hydrochloride (VHL Ligand-Linker Conjugates 4 hydrochloride
  • (2S,4R)-1-((S)-17-amino-2-(tert-butyl)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
  • (2R,4S)-1-((R)-17-amino-2-(tert-butyl)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
  • (2S,4R)-1-[(2S)-2-[[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
  • (S, R, S)-AHPC-PEG4-amine
  • VHL032-keto-PEG4-C2-amine HCl
  • (S,R,S)-AHPC-PEG4-NH2 HCl
  • 2064292-52-8