1-PALMITOYL-2-OLEOYL-SN-GLYCERO-3-[PHOSPHO-L-SERINE](SODIUM SALT)
- Product Name
- 1-PALMITOYL-2-OLEOYL-SN-GLYCERO-3-[PHOSPHO-L-SERINE](SODIUM SALT)
- CAS No.
- 321863-21-2
- Chemical Name
- 1-PALMITOYL-2-OLEOYL-SN-GLYCERO-3-[PHOSPHO-L-SERINE](SODIUM SALT)
- Synonyms
- PS(16：0/18：1(9Z));16:0-18:1 PS (POPS);DOPE PEG(2000)-N-Cy5;1,2-POPS sodium salt;16:0-18:1 PS (SODIUM SALT);2-OLEOYL-1-PALMITOYL-SN-GLYCERO-3-PH;3-sn-Phosphatidyl-L-serine, 2-oleoyl-1-palmi;1-Palmitoyl-2-oleoyl-sn-glycero-3-PS (sodium salt);2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium salt;1-PALMITOYL-2-OLEOYL-SN-GLYCERO-3-[PHOSPHO-L-SERINE](SODIUM SALT)
- CBNumber
- CB1347944
- Molecular Formula
- C40H77NNaO10P
- Formula Weight
- 786.02
- MOL File
- Mol file
1-PALMITOYL-2-OLEOYL-SN-GLYCERO-3-[PHOSPHO-L-SERINE](SODIUM SALT) Property
- storage temp.
- -20°C
- solubility
- Chloroform: 1 mg/ml
- form
- powder or crystals
- color
- White to off-white
- biological source
- synthetic
- InChIKey
- RQYKXRYGZHMUSU-JEAFVVATSA-M
- SMILES
- [H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]
Safety
- WGK Germany
- 3
- Storage Class
- 11 - Combustible Solids
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H336May cause drowsiness or dizziness
H351Suspected of causing cancer
H372Causes damage to organs through prolonged or repeated exposure
H412Harmful to aquatic life with long lasting effects
- Precautionary statements
-
P201Obtain special instructions before use.
P273Avoid release to the environment.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P308+P313IF exposed or concerned: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 51581
- Product name
- 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium salt
- Purity
- ≥75% (TLC)
- Packaging
- 100mg
- Price
- $361
- Updated
- 2022/05/15
- Product number
- 51581
- Product name
- 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium salt
- Purity
- ≥75% (TLC)
- Packaging
- 1g
- Price
- $2540
- Updated
- 2022/05/15
- Product number
- O532720
- Product name
- 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium salt
- Packaging
- 100mg
- Price
- $305
- Updated
- 2021/12/16
- Product number
- AAA0006685
- Product name
- 1-HEXADECANOYL-2-(CIS-9-OCTADECENOYL)-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.95
- Updated
- 2021/12/16
1-PALMITOYL-2-OLEOYL-SN-GLYCERO-3-[PHOSPHO-L-SERINE](SODIUM SALT) Chemical Properties,Usage,Production
Uses
Forms negatively charged lipid bilayers. A molecular dynamics simulation indicates that Na+ ions penetrate unexpectedly far into the bilayer, well beyond the hydrophilic end groups.
Uses
2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine Sodium Salt is a reagent that triggered the release of 5-Aminolevulinic acid (5-ALA) from stealth liposomes. A negatively charged membrane lipid.
General Description
Phosphoserine/phosphatidylserine (PS) is an endogenous phospholipid, that is found in all polyanionic macromolecules.
Biochem/physiol Actions
Phosphoserine(PS) can be used as a template for the recognition of cancer antigen 125 (CA 125). It is very essential for healthy nerve cell membranes and myelin. Exogenous PS can be actively absorbed in humans. It has the ability to cross the blood-brain barrier. It plays a key role in the formation of short-term memory, the ability to create new memories, to focus attention, to reason and solve problems and several other cognitive activities. It actively participates in the locomotor functions, like rapid reactions and reflexes.
References
[1] VITALII I. SILIN David P H. pH dependent electrical properties of the inner- and outer- leaflets of biomimetic cell membranes[J]. Journal of Colloid and Interface Science, 2021, 594: Pages 279-289. DOI: 10.1016/j.jcis.2021.03.016
[2] MINZHI YU Troy H Kristen Hong Dorsey, ANNA SCHWENDEMAN* Enhancement of Anti-inflammatory Effects of Synthetic High-Density Lipoproteins by Incorporation of Anionic Lipids[J]. Molecular Pharmaceutics, 2023, 20 11: 5454-5462. DOI: 10.1021/acs.molpharmaceut.3c00175
1-PALMITOYL-2-OLEOYL-SN-GLYCERO-3-[PHOSPHO-L-SERINE](SODIUM SALT) Preparation Products And Raw materials
Raw materials
Preparation Products
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