N-BENZOYL-4-PIPERIDONE
- Product Name
- N-BENZOYL-4-PIPERIDONE
- CAS No.
- 24686-78-0
- Chemical Name
- N-BENZOYL-4-PIPERIDONE
- Synonyms
- NSC 97564;N-BENZOYLPIPERIDONE;N-Benzoylpiperidinone;1-BENZOYL-4-PIPERIDONE;N-BENZOYL-4-PIPERIDONE;N-benzoylpiperidine-one;1-Benzoyl-piperidinoine;N-Benzoylpiperidone 98%;1-Benzoyl-4-piperidinone;4-Piperidone, 1-benzoyl-
- CBNumber
- CB1349049
- Molecular Formula
- C12H13NO2
- Formula Weight
- 203.24
- MOL File
- 24686-78-0.mol
N-BENZOYL-4-PIPERIDONE Property
- Melting point:
- 55-59 °C (lit.)
- Boiling point:
- 158-160 °C/0.2 mmHg (lit.)
- Density
- 1.1255 (rough estimate)
- refractive index
- 1.5440 (estimate)
- Flash point:
- >230 °F
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- methylene chloride: soluble
- pka
- -1.45±0.20(Predicted)
- form
- powder to crystal
- color
- White to Light yellow
- BRN
- 158848
- InChI
- 1S/C12H13NO2/c14-11-6-8-13(9-7-11)12(15)10-4-2-1-3-5-10/h1-5H,6-9H2
- InChIKey
- NZAXGZYPZGEVBD-UHFFFAOYSA-N
- SMILES
- O=C1CCN(CC1)C(=O)c2ccccc2
- CAS DataBase Reference
- 24686-78-0(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B3778
- Product name
- 1-Benzoyl-4-piperidone
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $78
- Updated
- 2024/03/01
- Product number
- B3778
- Product name
- 1-Benzoyl-4-piperidone
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $311
- Updated
- 2024/03/01
- Product number
- B700573
- Product name
- 1-Benzoylpiperidin-4-one
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR9378
- Product name
- 1-Benzoylpiperidin-4-one
- Purity
- 98%
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
- Product number
- 4H48-1-G7
- Product name
- 1-Benzoylpiperidin-4-one
- Purity
- 98.0%
- Packaging
- 1g
- Price
- $16
- Updated
- 2021/12/16
N-BENZOYL-4-PIPERIDONE Chemical Properties,Usage,Production
Chemical Properties
light yellow granular powder or granules
Uses
1-Benzoyl-4-piperidone can be used as starting reagent in the synthesis of fentanyl.
Biochem/physiol Actions
1-Benzoyl-4-piperidone and 1-methyl-4-piperidone reacts with triethyl phosphono-acetate in the presence of excess base and yields both the endocyclic and exocyclic olefins.
Synthesis
4-Piperidone hydrochloride hydrate (7.68 kg) with potassium carbonate (20.7 kg), 0 ?? C., added to water (50 liters), stirred well, then added to dichloromethane (40 liters), and then added dropwise to a solution of benzoyloxycarbonylsuccinimide (12.4 kg) of dichloromethane (80 liters), and the reaction was carried out at room temperature for two hours. The reaction solution was partitioned and the aqueous layer was extracted with dichloromethane (2 x 15 liters), the organic phases were combined, dried over anhydrous sodium sulfate, and concentrated to give 11.5 kg of 1-benzoyl-4-piperidone in the form of a colorless oil.
N-BENZOYL-4-PIPERIDONE Preparation Products And Raw materials
Raw materials
Preparation Products
N-BENZOYL-4-PIPERIDONE Suppliers
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View Lastest Price from N-BENZOYL-4-PIPERIDONE manufacturers
- Product
- N-BENZOYL-4-PIPERIDONE 24686-78-0
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-10-16
- Product
- N-BENZOYL-4-PIPERIDONE 24686-78-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- N-BENZOYL-4-PIPERIDONE 24686-78-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-08