ChemicalBook > CAS DataBase List > 1-Acetyl-2-imidazolidinone

1-Acetyl-2-imidazolidinone

Uses

Product Name: 1-Acetyl-2-imidazolidinone
CAS No.: 5391-39-9
Chemical Name: 1-Acetyl-2-imidazolidinone
Synonyms: RARECHEM AQ NN 0041;ACETYL IMIDAZO-2-ONE;Clonidine Impurity A;Acetyl Ethylene Urea;Clonidine EP Impurity A;N-Acetylimidazolidinone;Clonidine IMpurity-A(BP);1-Acetyl-2-Imidazolidone;1-acetyl-2-imidazolidine;1-ACETYL-2-IMIDAZOLIDINONE
CBNumber: CB1370702
Molecular Formula: C5H8N2O2
Formula Weight: 128.13
MOL File: 5391-39-9.mol

Less

1-Acetyl-2-imidazolidinone Property

Melting point:: 173-175°C
Density: 1.237
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Sparingly), DMSO (Sparingly), Methanol (Slightly, Heated)
form: Solid
pka: 12.11±0.20(Predicted)
color: White to Off-White
InChI: InChI=1S/C5H8N2O2/c1-4(8)7-3-2-6-5(7)9/h2-3H2,1H3,(H,6,9)
InChIKey: JJWACYUTERPMBM-UHFFFAOYSA-N
SMILES: C1(=O)N(C(C)=O)CCN1
CAS DataBase Reference: 5391-39-9(CAS DataBase Reference)

Less

Safety

HS Code: 2933.29.9000

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: R593206
Product name: 1-ACETYL-2-IMIDAZOLIDINONE
Purity: Aldrich<sup>CPR</sup>
Packaging: 1 unit
Price: $185
Updated: 2025/07/31

Sigma-Aldrich

Product number: R593206
Product name: 1-ACETYL-2-IMIDAZOLIDINONE
Purity: AldrichCPR
Packaging: 50MG
Price: $179
Updated: 2024/03/01

TCI Chemical

Product number: A1945
Product name: 1-Acetyl-2-imidazolidinone
Purity: >98.0%(GC)
Packaging: 5g
Price: $41
Updated: 2025/07/31

TCI Chemical

Product number: A1945
Product name: 1-Acetyl-2-imidazolidinone
Purity: >98.0%(GC)
Packaging: 25g
Price: $203
Updated: 2025/07/31

TRC

Product number: A167955
Product name: 1-Acetyl-2-imidazolidinone
Packaging: 25g
Price: $305
Updated: 2021/12/16

Less

1-Acetyl-2-imidazolidinone Chemical Properties,Usage,Production

Uses

1-Acetyl-2-imidazolidinone (Clonidine EP Impurity A) is a synthetic reagent used in the preparation of triple [14C]-labelled moxonidine which is an antihypertensive compound.

Uses

1-Acetyl-2-imidazolidinone (Clonidine EP Impurity A) is a synthetic reagent used in the preparation of triple [14C]-labelled moxonidine which is an antihypertensive compound.

Synthesis

120-93-4

108-24-7

5391-39-9

General procedure for the synthesis of 1-acetyl-2-imidazolidinone from 2-imidazolidinone and acetic anhydride: 5.18 g (60.2 mmol) of 2-imidazolidinone and 50 mL of acetic anhydride were added to a 100 mL round-bottom flask. The mixture was placed in an oil bath and the reaction was stirred at 150 °C for 1 hour. Upon completion of the reaction, the mixture was cooled to room temperature and filtered to collect the precipitated solid. The solid was washed with a small amount of cold ethanol to give a final 4.94 g (yield: 64.1%) of colorless solid 1-acetyl-2-imidazolidinone.

References

[1] Chemistry - A European Journal, 2002, vol. 8, # 11, p. 2464 - 2475
[2] Patent: JP2016/145198, 2016, A. Location in patent: Paragraph 0087-0089
[3] Arkivoc, 2014, vol. 2014, # 2, p. 44 - 56
[4] Journal of the American Chemical Society, 1958, vol. 80, p. 6409,6412

1-Acetyl-2-imidazolidinone Preparation Products And Raw materials

Raw materials

Preparation Products

Less

1-Acetyl-2-imidazolidinone Suppliers

Americas 1 Belgium 1 Canada 4 China 273 Czech Republic 1 Europe 4 Germany 7 India 25 Japan 3 South Korea 1 United Kingdom 10 United States 34 Global 364

Wuhan penglei Biotechnology Co., Ltd

Tel: 15871464247
Email: 1545569349@QQ.COM
Country: China
ProdList: 734
Advantage: 58

Henan Evonik Biotechnology Co. LTD

Tel: 15672878902
Email: hnyingchuang@163.com
Country: China
ProdList: 3905
Advantage: 58

Creasyn Finechem(Tianjin) Co., Ltd.

Tel: 022-83946278 13820503911
Fax: 022-83945176
Email: sales@creasyn.com
Country: China
ProdList: 957
Advantage: 68

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 2806
Advantage: 65

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768836
Email: 1791901229@qq.com
Country: China
ProdList: 6950
Advantage: 52

Beijing Isomersyn Technology CO;LTD

Tel: 010-82954736 13391601435
Email: sales@isomersyn.com
Country: China
ProdList: 3295
Advantage: 57

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Wuhan Fortuna Chemical Co., Ltd

Tel: 027-59207852 13308628970
Fax: QQ3130921841
Email: buy@fortunachem.com
Country: China
ProdList: 2745
Advantage: 58

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9895
Advantage: 58

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
Fax: 0755 28094224
Email: 3001272453@qq.com
Country: China
ProdList: 5158
Advantage: 50

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

China Nobel Chem Co., Limited

Tel: +86(0)21 60484900
Fax: +86(0)21 60484900
Country: China
ProdList: 764
Advantage: 50

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8026
Advantage: 55

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

Quzhou Juhua Friendship Co., Ltd

Tel: 0570-3066667
Fax: 0570-3063388
Country: China
ProdList: 3930
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Shanghai Worldyang Chemical Co.,Ltd.

Tel: 021-021-56795766
Fax: +86-21-56795266
Email: sales@worldyachem.com
Country: China
ProdList: 9476
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18333
Advantage: 56

Chengdu HuaXia Chemical Reagent Co. Ltd

Tel: 400-1166-196 13458535857
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 13350
Advantage: 58

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9906
Advantage: 50

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 14912
Advantage: 59

Nanjing Chalf-Pharm Technology Co., Ltd.

Tel: 025-57018978 18251899859
Fax: 025-57018008
Email: sales@chalf-pharm.com
Country: China
ProdList: 5674
Advantage: 50

Shanghai Tombiopharma Chemical Co. Ltd.

Tel: 13391076197
Email: tombiopharma@163.com
Country: China
ProdList: 4987
Advantage: 55

Credit Asia Chemical Co., Ltd.

Tel: +86 (21) 61124340
Fax: +86 (21) 6129-4103
Country: China
ProdList: 9756
Advantage: 58

Chengdu RunZeBenTu Chemical Co., Ltd

Tel: 028-88469284 18000562381
Email: rzbtsj@163.com
Country: China
ProdList: 9951
Advantage: 56

Qingxian Creasyn Pharmaceutical Technology Co., Ltd.

Tel: 022-83945173 18622315263
Fax: QQ1559208715
Email: export@creasyn.com
Country: China
ProdList: 490
Advantage: 55

ShangHai Siyan Biological Technology Co., Ltd.

Tel: 021-50908862，442785678，326799392 18721037013
Fax: 021-50908862
Email: siyansales@126.com
Country: China
ProdList: 9627
Advantage: 58

Henan CoreyChem Co., Ltd

Tel: 0371-86658258
Fax: 0371-60996044
Email: info@coreychem.com
Country: China
ProdList: 10453
Advantage: 58

Zhengzhou Alfachem Co.,Ltd.

Tel: 0371-53778726 18003825608
Fax: QQ：2885354392
Email: liuxiaoyan@alfachem.cn
Country: China
ProdList: 1986
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shanghai QianYan Bio-technology Co., Ltd

Tel: 02781293128
Email: orders@biochemsafebuy.com
Country: China
ProdList: 9923
Advantage: 55

Changzhou Hopschain Chemical Co.,Ltd.

Tel: 0519-85528066 13775048983
Fax: 0519-85528066
Email: sales@hopschem.com
Country: China
ProdList: 31553
Advantage: 55

parabiochem

Tel: 025-83453382-8005
Fax: 025-83453382
Email: sale@parabiochem.com
Country: China
ProdList: 9595
Advantage: 55

DoEasy Pharma Co., Ltd.

Tel: 0571-0571-28806358 15397199029
Fax: 0571-89057225
Email: songxy@doepharma.com
Country: China
ProdList: 82
Advantage: 55

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-0371-55629727 13323845623
Fax: 037155629727
Email: 2885676761@qq.com
Country: China
ProdList: 10110
Advantage: 58

Shenzhen Simeiquan Biotechnology Co. Ltd

Tel: 18126413629 0755-23311925 2355327053
Fax: 0755-23311925
Email: abel@ycgmp.com
Country: China
ProdList: 5113
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Guangdong wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2886750 13927877953
Fax: 0751-2886750
Email: 3005811397@qq.com
Country: China
ProdList: 13305
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Shenzhen Sendi Biological Technology Co., Ltd.

Tel: 18124570582 TEL：0755-23574479 2355327139
Fax: 0755-23229476 QQ: 2355327139
Email: siliao02@yccreate.com
Country: China
ProdList: 6116
Advantage: 58

Guangzhou Kafen Biotech Co.,Ltd

Tel: 18029243487 2355327168
Fax: 020-31121510
Email: gy@yccreate.com
Country: China
ProdList: 4749
Advantage: 55

Wuhai Shuou Technology Co., Ltd.

Tel: 17792809151
Fax: 18872220797
Email: 2355916837@ycphar.com
Country: China
ProdList: 6133
Advantage: 55

Nanjing BAM Biomedical Technology Co., Ltd.

Tel: 18066080842 13952020641
Fax: 025-58912720
Email: bamd@foxmail.com
Country: China
ProdList: 759
Advantage: 55

Less

View Lastest Price from 1-Acetyl-2-imidazolidinone manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 1-Acetyl-2-imidazolidinone 5391-39-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-03

Hebei Chuanghai Biotechnology Co., Ltd

Product: 1-Acetyl-2-imidazolidinone 5391-39-9
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-26

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 1-Acetylimidazolidin-2-one 5391-39-9
Price: US $75.00-25.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-05-28

5391-39-9, 1-Acetyl-2-imidazolidinone Related Search:

Imidazolidine Acetylacetone Imidazolidinyl urea Acetyl coenzyme A sodium salt N-ACETYL-L-TYROSINE ETHYL ESTER Acetyl chloride Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) 1,3-Dimethyl-2-imidazolidinone 2-Imidazolidone N-Carbethoxy-4-piperidone N-(tert-Butoxycarbonyl)-4-piperidone N-ACETYL-(2S)-BORNANE 10,2-SULTAM 1-Acetyl-5-broMo-6-chloro-1H-indol-3-yl acetate 6-CHLOROINDOXYL-1,3-DIACETATE AC-GLU-OME N-ACETYL-4-S-CYSTEAMINYLPHENOL 1-ACETYL-5-BROMO-7-NITROINDOLINE 1-acetyl-3-bromopiperidin-4-one hydrobromide

1-ethanoylimidazolidin-2-one

N-acetyl-2-iMidazolidazolidinone

Clonidine IMpurity-A(BP)

Clonidine Impurity A

2-Imidazolidinone,1-acetyl-

n-acetyl-2-imidazolidinone

RARECHEM AQ NN 0041

ACETYL IMIDAZO-2-ONE

1-ACETYL-IMIDAZOLIDIN-2-ONE

1-ACETYL-1,3,4,5-TETRAHYDROIMIDAZOLE-2-ONE

1-ACETYL-2-IMIDAZOLIDINONE

1-Acetyl-2-Imidazolidone

1-acetylimidazolidine-2-thione

Acetyl Ethylene Urea

1-acetyl-2-imidazolidine

1-acetyl-2-imidazol-1-iumone

Clonidine Impurity 1（Clonidine EP Impurity A)

Clonidine EP Impurity A

1-Acetyl-2-imidazolidinone &gt

N-Acetylimidazolidinone

Clonidine Hydrochloride EP Impurity A

Clonidine EP Impurity A 1-Acetylimidazolidin-2-one

Clonidine Hydrochloride Impurity A

5391-39-9

5391-53-9

C5H8N2O2

Imidazol&Benzimidazole

(intermediate of moxonidine hcl)