2,2,6,6-Tetramethyl-3,5-heptanedione

Product Name: 2,2,6,6-Tetramethyl-3,5-heptanedione
CAS No.: 1118-71-4
Chemical Name: 2,2,6,6-Tetramethyl-3,5-heptanedione
Synonyms: TMHD;2,2,6,6-TETRAMETHYLHEPTANE-3,5-DIONE;DIPIVALOYLMETHANE;2,2,6,6-Tetramethyl heptanedione;2,2,6,6-Tetramethyl-3,5-heptadione;butan-1-ol,propan-2-ol,titanium;3,5-Heptanedione, 2,2,6,6-tetramethyl-;dpm-h;5-heptanedione;6-Tetramethyl-3
CBNumber: CB1373637
Molecular Formula: C11H20O2
Formula Weight: 184.28
MOL File: 1118-71-4.mol

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2,2,6,6-Tetramethyl-3,5-heptanedione Property

Melting point:: >400 °C (decomp)
Boiling point:: 72-73 °C/6 mmHg (lit.)
Density: 0.883 g/mL at 25 °C (lit.)
refractive index: n20/D 1.459(lit.)
Flash point:: 153 °F
storage temp.: Sealed in dry,Room Temperature
solubility: Difficult to mix.
form: Liquid
pka: 11.60±0.10(Predicted)
Specific Gravity: 0.883
color: Clear colorless to slightly yellow
BRN: 1447269
InChIKey: YRAJNWYBUCUFBD-UHFFFAOYSA-N
LogP: 2.818 (est)
CAS DataBase Reference: 1118-71-4(CAS DataBase Reference)
EPA Substance Registry System: 3,5-Heptanedione, 2,2,6,6-tetramethyl- (1118-71-4)

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Safety

Hazard Codes: Xn
Risk Statements: 22-40-36/37/38
Safety Statements: 24/25-36-26-22
RIDADR: UN 1993 / PGIII
WGK Germany: 3
TSCA: T
HS Code: 29141900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

H302Harmful if swallowed

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 155756
Product name: 2,2,6,6-Tetramethyl-3,5-heptanedione
Purity: 98%
Packaging: 5g
Price: $49.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: 155756
Product name: 2,2,6,6-Tetramethyl-3,5-heptanedione
Purity: 98%
Packaging: 25g
Price: $144
Updated: 2024/03/01

TCI Chemical

Product number: D1678
Product name: Dipivaloylmethane
Purity: >97.0%(GC)
Packaging: 5g
Price: $61
Updated: 2024/03/01

TCI Chemical

Product number: D1678
Product name: Dipivaloylmethane
Purity: >97.0%(GC)
Packaging: 25g
Price: $173
Updated: 2024/03/01

Alfa Aesar

Product number: A15118
Product name: 2,2,6,6-Tetramethyl-3,5-heptanedione, 98%
Packaging: 5g
Price: $44.65
Updated: 2024/03/01

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2,2,6,6-Tetramethyl-3,5-heptanedione Chemical Properties,Usage,Production

Chemical Properties

CLEAR COLOURLESS TO SLIGHTLY YELLOW LIQUID

Uses

suzuki reaction

Uses

2,2,6,6-tetramethyl-3,5-heptanedione was used in the synthesis of α-aryl-β-diketones1 and dicyanamidobenzene-bridge diruthenium complex.

Uses

2,2,6,6-Tetramethyl-3,5-heptanedione is a beta diketone with antibacterial activity.

Definition

2,2,6,6-Tetramethyl-3,5-heptanedioneis a stable, anhydrous reagent. It undergoes O-additions and C-additions. In various reactions, it acts as an air-stable ligand for metal catalysts. Furthermore, it serves as a substrate for heterocycles.

Synthesis Reference(s)

Journal of the American Chemical Society, 100, p. 5428, 1978 DOI: 10.1021/ja00485a030

General Description

Acylation, a replacement to silylation, allows the conversion of compounds that consist of active hydrogens (-OH, -SH and -NH) into esters, thioesters, and amides via the action of a carboxylic acid or derivative. The carbonyl group adjacent to the halogenated carbons is known to improve the electron capture detector (ECD) response. Acylation has several advantages:

It enhances the stability of compounds by protecting unstable groups.
It may confer volatility on substances like carbohydrates or amino acids, that have several polar groups that they are non-volatile and usually decompose on heating.
It facilitates the separations not possible with underivatized compounds.
Compounds are detectable at very low levels with an ECD.

2,2,6,6-Tetramethyl-3,5-heptanedione is a reagent used to form fragmentation-directing derivatives for GC/MS analysis.

Synthesis

Methyl pivalate and formamide could be used as starting materials to synthesize 2,2,6,6-Tetramethyl-3,5-heptanedione.

2,2,6,6-Tetramethyl-3,5-heptanedione Preparation Products And Raw materials

Raw materials

Sodium hydride Ethanol N,N-Dimethylformamide Pinacolone Tetrahydrofuran Diethyl ether Ethyl acetate Methyl trimethylacetate Hydrochloric acid

Preparation Products

N,N-DIPHENYLQUINACRIDONE

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2,2,6,6-Tetramethyl-3,5-heptanedione Suppliers

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View Lastest Price from 2,2,6,6-Tetramethyl-3,5-heptanedione manufacturers

Speranza Chemical Co., Ltd.

Product: 2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE 1118-71-4
Price: US $205.00-195.00/KG
Min. Order: 25KG
Purity: 98%
Supply Ability: 500kg
Release date: 2023-11-29

Hebei Weibang Biotechnology Co., Ltd

Product: 2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE 1118-71-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-28

Hebei Yanxi Chemical Co., Ltd.

Product: 2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE 1118-71-4
Price: US $40.00-13.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-09-13

1118-71-4, 2,2,6,6-Tetramethyl-3,5-heptanedioneRelated Search:

2,4-HEXANEDIONE 2,2,6,6-Tetramethyl-3,5-heptanedione copper(II) derivative, Cu(TMHD)2,2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE, COPPER(II) DERIVATIVE 2,2,6,6-Tetramethyl-3,5-heptanedione 2,2-DIMETHYL-3,5-HEXANEDIONE 3,5-HEPTANEDIONE Barium bis(2,2,6,6-tetramethyl-3,5-heptanedionate) hydrate TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) BIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)LEAD(II) GD(TMHD)3 BIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)LEAD(II) 2,2-DIMETHYL-3-HEXANONE 2,6-DIMETHYL-3,5-HEPTANEDIONE BISMUTH TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATE) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)YTTRIUM(III) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)YTTERBIUM 2,6-HEPTANEDIONE 2,2-DIMETHYL-3-HEPTANONE 4,4-DIMETHYL-3-OXO-PENTANAL

(CH3)3CCOCH2COC(CH3)3

2,2,6,6-Tetramethyl heptanedione

2,2,6,6-tetramethyl-5-heptanedione

TMHD

DIPIVALOYLMETHANE

2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE DIPIVALOYLMETHANE

2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE

2,2,6,6-TETRAMETHYLHEPTANE-3,5-DIONE

Dipivaloylmethane~Dpm-H~Tmhd-H

2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE, 95 %

2,2,6,6-Tetramethylheptane-3,5-dione,98%TMHD

3,5-Heptanedione, 2,2,6,6-tetramethyl-

dpm-h

2,2,6,6-TETRAMETHYLHEPTANE-3,5-DIONE TMHD

2,2,6,6-Tetramethyl-3,5-heptanedione, 99+%

2,2,6,6-Tetramethyl-3,5-heptanedione, 98+%

2,2,6,6-Tetramethyl-3,5-heptadione

1,3-Di-tert-butyl-1,3-propanedione

2,2,6,6-Tetramethylheptane-3,5-dione, 99% TMHD

2,2,6,6-TetraMethyl-3,5-heptanedione, 98% 5GR

2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONE FOR

2,2,6,6-TetraMethyl-3,5-heptan

Dipivaloylmethane, 3,5-Dioxo-2,2,6,6-tetramethylheptane

2,2,6,6-TetraMethylheptane-3,5-dione SynonyMs 1,3-Di-tert-butyl-1,3-propanedione

2,2,6,6-Tetramethylheptane-3,5-dione 98%

5-heptanedione

6-Tetramethyl-3

Dipivaloylmethane&gt

DIPIVALOYALMETHANE

-3,5-heptanedione

butan-1-ol,propan-2-ol,titanium

2,2,6,6-Tetramethylheptane-3,5-dione 1118-71-4

1118-71-4

11188-71-4

C11H20O2

KETONE

Ligands (Environmentally-friendly Oxidation)

Environmentally-friendly Oxidation

C11 to C12

Carbonyl Compounds

Acylation

Building Blocks

Organic Building Blocks

Ketones

Achiral Oxygen

organic compound

Environmentally-friendly Oxidation

Ligands (Environmentally-friendly Oxidation)

Synthetic Organic Chemistry

CHIRAL CHEMICALS