ChemicalBook > CAS DataBase List > (E)-2-((5-(4-nitrophenyl)furan-2-yl)methylene)hydrazine-1-carbothioamide
(E)-2-((5-(4-nitrophenyl)furan-2-yl)methylene)hydrazine-1-carbothioamide
- Product Name
- (E)-2-((5-(4-nitrophenyl)furan-2-yl)methylene)hydrazine-1-carbothioamide
- CAS No.
- 1632320-78-5
- Chemical Name
- (E)-2-((5-(4-nitrophenyl)furan-2-yl)methylene)hydrazine-1-carbothioamide
- Synonyms
- F8-S43-S3;(2E)-2-{[5-(4-nitrophenyl)furan-2-yl]methylidene}hydrazinecarbothioamide;(E)-2-((5-(4-nitrophenyl)furan-2-yl)methylene)hydrazine-1-carbothioamide;Hydrazinecarbothioamide, 2-[[5-(4-nitrophenyl)-2-furanyl]methylene]-, (2E)-
- CBNumber
- CB13910273
- Molecular Formula
- C12H10N4O3S
- Formula Weight
- 290.3
- MOL File
- 1632320-78-5.mol
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(E)-2-((5-(4-nitrophenyl)furan-2-yl)methylene)hydrazine-1-carbothioamide Property
- Boiling point:
- 496.6±55.0 °C(Predicted)
- Density
- 1.48±0.1 g/cm3(Predicted)
- pka
- 11.20±0.70(Predicted)
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(E)-2-((5-(4-nitrophenyl)furan-2-yl)methylene)hydrazine-1-carbothioamide Chemical Properties,Usage,Production
Uses
F8-S43-S3 is an inhibitor of SARS-CoV-2 main protease, with an IC50 of 9.69 μM[1].
References
[1] Dou X, et, al. Discovery of 2-(furan-2-ylmethylene)hydrazine-1-carbothioamide derivatives as novel inhibitors of SARS-CoV-2 main protease. Eur J Med Chem. 2022 Aug 5;238:114508. DOI:10.1016/j.ejmech.2022.114508
(E)-2-((5-(4-nitrophenyl)furan-2-yl)methylene)hydrazine-1-carbothioamide Preparation Products And Raw materials
Raw materials
Preparation Products
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(E)-2-((5-(4-nitrophenyl)furan-2-yl)methylene)hydrazine-1-carbothioamide Suppliers
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