ChemicalBook > CAS DataBase List > 4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid
4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid
- Product Name
- 4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid
- CAS No.
- 351424-20-9
- Chemical Name
- 4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid
- Synonyms
- TRPM4-IN-1;TRPM4-IN-5;CBA (TRPM4-IN-5);TRPM4 inhibitor 5;TRPM4-IN-1, 10 mM in DMSO;4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid;4-Chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]benzoic acid;Benzoic acid, 4-chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]-;TRP Channel,Transient receptor potential channels,non-selective,TRPM4IN1,diseases,TRPM4,inhibit,Inhibitor,TRPM-4-IN-1,TRPM4 IN 1,cancer,cation,cardiac,channel,prostate,calcium-activated
- CBNumber
- CB14112210
- Molecular Formula
- C15H11Cl2NO4
- Formula Weight
- 340.16
- MOL File
- 351424-20-9.mol
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4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- A solid
- color
- White to yellow
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0087435
- Product name
- TRPM4-IN-1
- Purity
- 99.91%
- Packaging
- 10mg
- Price
- $70
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0087435
- Product name
- TRPM4-IN-1
- Purity
- 99.91%
- Packaging
- 25mg
- Price
- $150
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0087435
- Product name
- TRPM4-IN-1
- Purity
- 99.91%
- Packaging
- 50mg
- Price
- $250
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0087435
- Product name
- TRPM4-IN-1
- Purity
- 99.91%
- Packaging
- 100mg
- Price
- $400
- Updated
- 2021/12/16
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4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid Chemical Properties,Usage,Production
Uses
TRPM4-IN-1 (CBA) is a potent and selective inhibitor of the cation channel TRPM4, with an IC50 of 1.5 μM. TRPM4-IN-1 can be used for the research of cardiac diseases and prostate cancer[1][2].
storage
Store at -20°C
References
[1] Lijo Cherian Ozhathil, et al. Identification of potent and selective small molecule inhibitors of the cation channel TRPM4. Br J Pharmacol. 2018 Jun; 175(12): 2504–2519. DOI:10.1111/bph.14220
[2] Clémence Delalande, et al. Optimizing TRPM4 inhibitors in the MHFP6 chemical space. Eur J Med Chem. 2019 Mar 15;166:167-177. DOI:10.1016/j.ejmech.2019.01.048
4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid Suppliers
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