DL-CATECHIN
- Product Name
- DL-CATECHIN
- CAS No.
- 88191-48-4
- Chemical Name
- DL-CATECHIN
- Synonyms
- CATECHU;CATECHIN;CATECHINS;DL-CATECHIN;CATECHIN, DL-;(+/-)-CATECHIN;(-)-CYANIDANOL-3;dl-Catechin Hydrate;DL-CATECHIN CATECHINS;TRANS-PYROMELLITIC ACID
- CBNumber
- CB1428151
- Molecular Formula
- C15H16O7
- Formula Weight
- 308.29
- MOL File
- 88191-48-4.mol
DL-CATECHIN Property
- storage temp.
- 2-8°C
- CAS DataBase Reference
- 88191-48-4(CAS DataBase Reference)
Safety
- WGK Germany
- 3
- F
- 10
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- PXT0000027
- Product name
- DL-CATECHIN
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $904.71
- Updated
- 2021/12/16
- Product number
- 16417
- Product name
- (+)-CATECHIN
- Purity
- >98%
- Packaging
- 25mg
- Price
- $930
- Updated
- 2021/12/16
DL-CATECHIN Chemical Properties,Usage,Production
Uses
Catechin hydrate inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
Definition
ChEBI: The monohydrate of (+)-catechin.
in vivo
Animals treated with Catechin at the lowest tested dose, i.e., 50 mg/kg, p.o. have spent comparatively more time in exploring the novel object in the choice trial, however, the difference is not statistically significant. Catechin prevents the time-induced episodic memory deficits in a dose-dependent manner, the most effective being 200 mg/kg, p.o.. Treatment with Catechin prevents the rise in MPO level compare to DOX alone treatment group (21.98±9.44 and 36.76±4.39% in the hippocampus and the frontal cortex respectively)[3].
IC 50
COX-1: 1.4 μM (IC50)
References
[1] Waffo-Téguo P, et al. Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. Nutr Cancer. 2001;40(2):173-9. DOI:10.1207/S15327914NC402_14
[2] Alshatwi AA. Catechin hydrate suppresses MCF-7 proliferation through TP53/Caspase-mediated apoptosis. J Exp Clin Cancer Res. 2010 Dec 17;29:167. DOI:10.1186/1756-9966-29-167
[3] Cheruku SP, et al. Catechin ameliorates doxorubicin-induced neuronal cytotoxicity in in vitro and episodic memory deficit in in vivo in Wistar rats. Cytotechnology. 2018 Feb;70(1):245-259. DOI:10.1007/s10616-017-0138-8
DL-CATECHIN Preparation Products And Raw materials
Raw materials
Preparation Products
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