2,5-OXAZOLIDINEDIONE
Uses- Product Name
- 2,5-OXAZOLIDINEDIONE
- CAS No.
- 2185-00-4
- Chemical Name
- 2,5-OXAZOLIDINEDIONE
- Synonyms
- GLY-NCA;L-Gly-NCA;2,5-OXAZOLIDINEDIONE;oxazolidine-2,5-dione;2,5-Oxazolidinedione 98%;1,3-oxazolidine-2,5-dione;GLYCINE-N-CARBOXYANHYDRIDE;N-Carboxyglycine anhydride
- CBNumber
- CB1432288
- Molecular Formula
- C3H3NO3
- Formula Weight
- 101.06
- MOL File
- 2185-00-4.mol
2,5-OXAZOLIDINEDIONE Property
- Melting point:
- 120 °C (dec.) (lit.)
- Density
- 1.469±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- pka
- 9.32±0.20(Predicted)
- form
- solid
- Appearance
- White to yellow Solid
- CAS DataBase Reference
- 2185-00-4
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- 369772
- Product name
- 2,5-Oxazolidinedione
- Purity
- 98%
- Packaging
- 1g
- Price
- $107.5
- Updated
- 2025/07/31
- Product number
- 369772
- Product name
- 2,5-Oxazolidinedione
- Purity
- 98%
- Packaging
- 5g
- Price
- $909
- Updated
- 2025/07/31
- Product number
- 094908
- Product name
- Oxazolidine-2,5-dione
- Purity
- 95+%
- Packaging
- 10g
- Price
- $977
- Updated
- 2021/12/16
- Product number
- 1066AB
- Product name
- Oxazolidine-2,5-dione
- Packaging
- 5g
- Price
- $477
- Updated
- 2021/12/16
- Product number
- CHM0019750
- Product name
- 2,5-OXAZOLIDINEDIONE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $668.23
- Updated
- 2021/12/16
2,5-OXAZOLIDINEDIONE Chemical Properties,Usage,Production
Uses
2,5-Oxazolidinone can be used as a pharmaceutical synthesis intermediate. Glycine-N-lactaloanhydride, valine-N-lactaloanhydride (2,5-Oxazolidinone), leucine-N-lactaloanhydride, or alanine-N-lactaloanhydride, these amphiphilic polyamino acids with hydrophilic and hydrophobic segments, can form nanoscale physical gels in water and can gel at certain temperatures. Therefore, these physical gels can serve as carrier materials for drug delivery and controlled release.
Preparation
Into a suspension of finely ground glycine (15 g) in dry dioxane (750 mL), phosgene was introduced in a fine stream at 45–50 °C with efficient agitation. A clear solution was obtained after 5 h. This solution was filtered to remove unreacted glycine (1.7 g), and the dioxane was then removed under reduced pressure at a temperature below 40 °C with protection from moisture. The residue was treated with dry diethyl ether (100 mL), and the crystals of 2,5-oxazolidinedione were collected by filtration and dried over P2O5 in a vacuum desiccator. The crude product so obtained, 16 g (89%), was recrystallized from ethyl acetate/petroleum ether to yield 14.3 g (77.2%) of pure material, which showed no melting point because of polymerization.
Preparation
Phosgene was passed in a fine stream into a suspension of finely ground glycine (15 g) in dry dioxane (750 mL) at 45–50 ℃ with efficient agitation. A clear solution was obtained after 5 h. This solution was filtered to remove unreacted glycine (1.7 g), and the dioxane was then removed under reduced pressure at a temperature below 40 ℃ under exclusion of moisture. The residue was treated with dry diethyl ether (100 mL), and the crystals of 2,5-oxazolidinedione were collected by filtration and dried over P2O5 in a vacuum desiccator. The crude product thus obtained, 16 g (89%), was recrystallized from ethyl acetate/petroleum ether to yield 14.3 g (77.2%) of pure material, which showed no melting point because of polymerization.
2,5-OXAZOLIDINEDIONE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,5-OXAZOLIDINEDIONE manufacturers
- Product
- Gly-NCA 2185-00-4
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2024-01-16
- Product
- 2,5-OXAZOLIDINEDIONE 2185-00-4
- Price
- US $6.68/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg-1000kg
- Release date
- 2020-01-08