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2,5-OXAZOLIDINEDIONE

Product Name
2,5-OXAZOLIDINEDIONE
CAS No.
2185-00-4
Chemical Name
2,5-OXAZOLIDINEDIONE
Synonyms
GLY-NCA;L-Gly-NCA;2,5-OXAZOLIDINEDIONE;oxazolidine-2,5-dione;2,5-Oxazolidinedione 98%;1,3-oxazolidine-2,5-dione;GLYCINE-N-CARBOXYANHYDRIDE;N-Carboxyglycine anhydride
CBNumber
CB1432288
Molecular Formula
C3H3NO3
Formula Weight
101.06
MOL File
2185-00-4.mol
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2,5-OXAZOLIDINEDIONE Property

Melting point:
120 °C (dec.) (lit.)
Density 
1.469±0.06 g/cm3(Predicted)
storage temp. 
-20°C
pka
9.32±0.20(Predicted)
CAS DataBase Reference
2185-00-4
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
369772
Product name
2,5-Oxazolidinedione
Purity
98%
Packaging
1g
Price
$208
Updated
2024/03/01
Sigma-Aldrich
Product number
369772
Product name
2,5-Oxazolidinedione
Purity
98%
Packaging
5g
Price
$713
Updated
2024/03/01
Matrix Scientific
Product number
094908
Product name
Oxazolidine-2,5-dione
Purity
95+%
Packaging
10g
Price
$977
Updated
2021/12/16
Matrix Scientific
Product number
094908
Product name
Oxazolidine-2,5-dione
Purity
95+%
Packaging
1g
Price
$227
Updated
2021/12/16
AK Scientific
Product number
1066AB
Product name
Oxazolidine-2,5-dione
Packaging
1g
Price
$172
Updated
2021/12/16
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2,5-OXAZOLIDINEDIONE Chemical Properties,Usage,Production

Preparation

Into a suspension of finely ground glycine (15 g) in dry dioxane (750 mL), phosgene was introduced in a fine stream at 45–50 °C with efficient agitation. A clear solution was obtained after 5 h. This solution was filtered to remove unreacted glycine (1.7 g), and the dioxane was then removed under reduced pressure at a temperature below 40 °C with protection from moisture. The residue was treated with dry diethyl ether (100 mL), and the crystals of 2,5-oxazolidinedione were collected by filtration and dried over P2O5 in a vacuum desiccator. The crude product so obtained, 16 g (89%), was recrystallized from ethyl acetate/petroleum ether to yield 14.3 g (77.2%) of pure material, which showed no melting point because of polymerization.

Preparation

Phosgene was passed in a fine stream into a suspension of finely ground glycine (15 g) in dry dioxane (750 mL) at 45–50 ℃ with efficient agitation. A clear solution was obtained after 5 h. This solution was filtered to remove unreacted glycine (1.7 g), and the dioxane was then removed under reduced pressure at a temperature below 40 ℃ under exclusion of moisture. The residue was treated with dry diethyl ether (100 mL), and the crystals of 2,5-oxazolidinedione were collected by filtration and dried over P2O5 in a vacuum desiccator. The crude product thus obtained, 16 g (89%), was recrystallized from ethyl acetate/petroleum ether to yield 14.3 g (77.2%) of pure material, which showed no melting point because of polymerization.

2,5-OXAZOLIDINEDIONE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,5-OXAZOLIDINEDIONE Suppliers

Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
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60
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
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China
ProdList
42958
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64
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
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China
ProdList
12984
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57
Shanghai Aladdin Bio-Chem Technology Co.,LTD
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400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
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China
ProdList
25003
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Shanghai DiBai Chemicals Co., Ltd.
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021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
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China
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3991
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Wuxi Zhongkun Biochemical Technology Co., Ltd.
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0510-85629785 18013409632
Fax
051085625359
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sales@reading-chemicals.com
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China
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15178
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Finetech Industry Limited
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027-87465837 19945049750
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027-8777-2287
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China
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Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770
Fax
0731-82251112
Email
viola@huatengsci.com
Country
China
ProdList
5873
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58
Shanghai Tombiopharma Chemical Co. Ltd.
Tel
13391076197
Email
tombiopharma@163.com
Country
China
ProdList
4987
Advantage
55
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
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View Lastest Price from 2,5-OXAZOLIDINEDIONE manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Gly-NCA 2185-00-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2024-01-16
Career Henan Chemical Co
Product
2,5-OXAZOLIDINEDIONE 2185-00-4
Price
US $6.68/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg-1000kg
Release date
2020-01-08