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ARG-LYS-ARG-ALA-ARG-LYS-GLU

Product Name
ARG-LYS-ARG-ALA-ARG-LYS-GLU
CAS No.
82801-73-8
Chemical Name
ARG-LYS-ARG-ALA-ARG-LYS-GLU
Synonyms
RKRARKE;PKG INHIBITOR;PKG Inhibitor,RKRARKE;PKG inhibitor peptide;PROTEIN KINASE G INHIBITOR;OUKSKNTVYYVIMZ-DUJSLOSMSA-N;[ALA32]-HISTONE H2B (29-35);ARG-LYS-ARG-ALA-ARG-LYS-GLU;Alg-Lys-Arg-Ala-Arg-Lys-Glu;H-ARG-LYS-ARG-ALA-ARG-LYS-GLU-OH
CBNumber
CB1437223
Molecular Formula
C38H74N18O10
Formula Weight
943.11
MOL File
82801-73-8.mol
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ARG-LYS-ARG-ALA-ARG-LYS-GLU Property

Density 
1.50±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Solid
pka
3.16±0.10(Predicted)
Water Solubility 
Soluble in water at 1mg/ml
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Alfa Aesar
Product number
J66858
Product name
Arg-Lys-Arg-Ala-Arg-Lys-Glu
Packaging
5mg
Price
$216
Updated
2021/12/16
Alfa Aesar
Product number
J66858
Product name
Arg-Lys-Arg-Ala-Arg-Lys-Glu
Packaging
1mg
Price
$81.8
Updated
2021/12/16
Cayman Chemical
Product number
15995
Product name
PKG Inhibitor
Purity
≥95%
Packaging
1mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
15995
Product name
PKG Inhibitor
Purity
≥95%
Packaging
5mg
Price
$262
Updated
2024/03/01
Cayman Chemical
Product number
15995
Product name
PKG Inhibitor
Purity
≥95%
Packaging
10mg
Price
$467
Updated
2024/03/01
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ARG-LYS-ARG-ALA-ARG-LYS-GLU Chemical Properties,Usage,Production

Description

PKG inhibitor is a specific cGMP-dependent PKG inhibitor (Ki = 86 μM). This synthetic peptide is a nonphosphorylatable analog of a substrate corresponding to the serine-32 phosphorylation site in histone H2B. PKG inhibitor has been reported to block cGMP-dependent NMDA potentiation and nitric oxide-induced depression of GABA currents in cultured retinal amacrine cells.

Uses

A reversible substrate competitive inhibitor for protein kinase G. The sequence corresponds to a non-phosphorylatable analog of histone H2B.

ARG-LYS-ARG-ALA-ARG-LYS-GLU Preparation Products And Raw materials

Raw materials

Preparation Products

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82801-73-8, ARG-LYS-ARG-ALA-ARG-LYS-GLURelated Search:


  • ARG-LYS-ARG-ALA-ARG-LYS-GLU: RKRARKE
  • ARG-LYS-ARG-ALA-ARG-LYS-GLU
  • H-ARG-LYS-ARG-ALA-ARG-LYS-GLU-OH
  • CGMP DEPENDENT KINASE INHIBITOR PEPTIDE
  • [ALA32]-HISTONE H2B (29-35)
  • PKG INHIBITOR
  • PROTEIN KINASE G INHIBITOR
  • RKRARKE
  • arginyl-lysyl-arginyl-alanyl-arginyl-lysyl-glutamic acid
  • cGMP-Dependent Protein Kinase Inhibitor Peptide
  • OUKSKNTVYYVIMZ-DUJSLOSMSA-N
  • Alg-Lys-Arg-Ala-Arg-Lys-Glu
  • L-Glutamic acid, L-arginyl-L-lysyl-L-arginyl-L-alanyl-L-arginyl-L-lysyl-
  • PKG Inhibitor,RKRARKE
  • PKG inhibitor peptide
  • 82801-73-8
  • C38H74N18O10
  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical
  • Protein Kinase G (PKG)
  • Kinase/Phosphatase Biology
  • Serine/Threonine Kinase Inhibitors
  • Protein Kinase