PAI-1

Product Name
PAI-1
Chemical Name
PAI-1
Synonyms
PAI-1;ARMAPE;PAI-1, RAT;MOUSE PAI-1;PAI-1, MOUSE;PAI-1, HUMAN;PAI-1, MUTANT, MOUSE;PLASMINOGEN ACTIVATOR INHIBITOR 1;PLASMINOGEN ACTIVATOR INHIBITOR-1, RAT;MOUSE PLASMINOGEN ACTIVATOR INHIBITOR-1
CBNumber
CB1438644
Molecular Formula
C27H47N9O9S
Formula Weight
673.78
MOL File
Mol file
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
528205
Product name
Plasminogen Activator Inhibitor-1, Human, Recombinant
Purity
The Plasminogen Activator Inhibitor-1, Human, Recombinant controls the biological activity of Plasminogen Activator. This small molecule/inhibitor is primarily used for Protease Inhibitors applicatio
Packaging
50μg
Price
$390
Updated
2024/03/01
Usbiological
Product number
027470
Product name
Plasminogen Activator Inhibitor 1
Packaging
96Tests
Price
$706
Updated
2021/12/16
Usbiological
Product number
156349
Product name
Plasminogen Activator Inhibitor 1
Packaging
10ug
Price
$333
Updated
2021/12/16
Usbiological
Product number
027469
Product name
Plasminogen Activator Inhibitor 1
Packaging
96Tests
Price
$851
Updated
2021/12/16
Usbiological
Product number
P4256-38
Product name
Plasminogen Activator Inhibitor Type 1, Mouse Assay Kit, BioAssay™
Packaging
1Kit
Price
$1042
Updated
2021/12/16
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PAI-1 Chemical Properties,Usage,Production

Enzyme inhibitor

This 402-residue serine protease inhibitor, or serpin (MW = 45074 g/mol; Abbreviation: PAI-1) binds to and inhibits plasminogen activators-tissuetype plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA). This inhibition reduces plasmin production and suppresses dissolution of fibrin clots. Elevated PAI-1 levels correlate with an increased cardiovascular disease risk, a behavior that has also been linked to obesity and metabolic syndrome. Pharmacological suppression of PAI-1 is a likely way to prevent or treat vascular disease. Reduced PAI-1 levels may result in increased fibrinolysis and an associated bleeding diathesis. PAI-1 was initially identified in the 1980s, and the first reported case of PAI-1 deficiency appeared in 1989. Unambiguous proof that PAI-1 deficiency as a cause of a bleeding disorder has been rare, but use of selective PAI inhibitors (See PAI-749) may clarify this point. Because of lack of standardized commercially available PAI-1 activity assay sensitive in the lowest range, the true prevalence of this rare condition has yet to be established.

PAI-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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PAI-1 Suppliers

Shanghai Yaji Biological Technology Co., Ltd.
Tel
021-34661275 15301693058
Email
yajikit@163.com
Country
China
ProdList
7140
Advantage
58
Shanghai Huzhen Industrial Co., LTD
Tel
021-60345367 13916550749
Email
sales@shzbio.com
Country
China
ProdList
9965
Advantage
58
Shenyang Wanji Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
sales@wanleibio.com
Country
CHINA
ProdList
389
Advantage
58
Guangzhou Ruiboao Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
info@raybiotech.com
Country
CHINA
ProdList
2408
Advantage
58
Beijing Bai Ao Si Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
yangmei@bioneeds.net
Country
CHINA
ProdList
6999
Advantage
58
Beijing Fubo Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
info@f-biology.com
Country
CHINA
ProdList
6039
Advantage
58
Shanghai Hao Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
shxiyuanbio@163.com
Country
CHINA
ProdList
6921
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6846
Advantage
58
Xi Shi Biotechnology (Shanghai) Co., Ltd.
Tel
--
Fax
--
Email
joanna.lu@csbiochina.com
Country
CHINA
ProdList
2590
Advantage
58
Shanghai Minmin Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1914109725@qq.com
Country
CHINA
ProdList
6530
Advantage
58
Beijing Huaxia Ocean Technology Co., Ltd.
Tel
--
Fax
--
Email
huaxiabio@163.com
Country
CHINA
ProdList
6122
Advantage
58
Cohesion Biosciences Limited
Tel
--
Fax
--
Email
custom@cohesionbio.com
Country
CHINA
ProdList
5350
Advantage
58
Beijing Bi Orange Blue Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
bo49855987@163.com
Country
CHINA
ProdList
6827
Advantage
58
Nanjing Shanben Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
sales@sciben.com
Country
CHINA
ProdList
6053
Advantage
58
Beijing Jiamei Nuno Biotechnology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
1820
Advantage
58
Xiamen Huijia Biological Technology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6979
Advantage
58
Shanghai Lianmai Biological Engineering Co., Ltd.
Tel
--
Fax
--
Email
shlmai@163.com
Country
CHINA
ProdList
6700
Advantage
58
Xiamen Research Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1562893815@qq.com
Country
CHINA
ProdList
6942
Advantage
58
BEIJING BIOSYNTHESIS BIOTECHNOLOGY CO., LTD.
Tel
--
Fax
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Email
sales@bioss.com.cn
Country
CHINA
ProdList
6717
Advantage
58
Guangzhou Weijia Technology Co., Ltd.
Tel
--
Fax
--
Email
WHIGA22@126.COM
Country
CHINA
ProdList
6748
Advantage
58
Shanghai Boyi Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
15800446246@163.com
Country
CHINA
ProdList
5417
Advantage
58

PAI-1Related Search:


  • ARMAPE
  • MOUSE PAI-1
  • MOUSE PLASMINOGEN ACTIVATOR INHIBITOR-1
  • PAI-1
  • PAI-1, HUMAN
  • PAI-1, MOUSE
  • PAI-1, MUTANT, MOUSE
  • PAI-1, RAT
  • PLASMINOGEN ACTIVATOR INHIBITOR-1, HUMAN
  • PLASMINOGEN ACTIVATOR INHIBITOR-1, HUMAN, RECOMBINANT
  • PLASMINOGEN ACTIVATOR INHIBITOR 1
  • PLASMINOGEN ACTIVATOR INHIBITOR-1, MUTANT, MOUSE
  • PLASMINOGEN ACTIVATOR INHIBITOR-1, MUTANT, MOUSE, RECOMBINANT
  • PLASMINOGEN ACTIVATOR INHIBITOR-1, RAT
  • PLASMINOGEN ACTIVATOR INHIBITOR-1, RAT, RECOMBINANT
  • Plasminogen Activator Inhibitor Type 1, active, Mouse Assay Kit, BioAssay&trade
  • Plasminogen Activator Inhibitor Type 1, active, Rat Assay Kit, BioAssay&trade
  • Plasminogen Activator Inhibitor Type 1, active, Human, Assay Kit, BioAssay&trade
  • Plasminogen Activator Inhibitor Type 1, active, Rabbit Assay Kit, BioAssay&trade
  • Plasminogen Activator Inhibitor Type 1, Mouse Assay Kit, BioAssay&trade
  • Plasminogen Activator Inhibitor Type 1, active, Porcine Assay Kit, BioAssay&trade
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