5-FLUOROBENZOFURAN

Product Name: 5-FLUOROBENZOFURAN
CAS No.: 24410-59-1
Chemical Name: 5-FLUOROBENZOFURAN
Synonyms: 5-FLUOROBENZOFURAN;5-Fluorobenzo[b]furan;5-Fluoro[b]benzofuran;Benzofuran, 5-fluoro-;5-fluoro-1-benzofuran;5-Fluorobenzo[b]furan 95+%
CBNumber: CB1445383
Molecular Formula: C8H5FO
Formula Weight: 136.12
MOL File: 24410-59-1.mol

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5-FLUOROBENZOFURAN Property

Boiling point:: 55 °C(Press: 11 Torr)
Density: 1.231±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Chloroform, DCM, Ethyl Acetate
form: Oil
color: Yellow
InChI: InChI=1S/C8H5FO/c9-7-1-2-8-6(5-7)3-4-10-8/h1-5H
InChIKey: FTVHMXRCGNWCOL-UHFFFAOYSA-N
SMILES: O1C2=CC=C(F)C=C2C=C1

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Safety

HS Code: 2932990090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: F588555
Product name: 5-Fluorobenzofuran
Packaging: 250mg
Price: $275
Updated: 2021/12/16

Apolloscientific

Product number: PC48599
Product name: 5-Fluorobenzo[b]furan
Purity: 95%
Packaging: 250mg
Price: $250
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2H10-3-25
Product name: 5-Fluorobenzo[b]furan
Packaging: 250mg
Price: $400
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0354839
Product name: 5-FLUOROBENZOFURAN
Purity: 95.00%
Packaging: 5MG
Price: $499.69
Updated: 2021/12/16

Apolloscientific

Product number: PC48599
Product name: 5-Fluorobenzo[b]furan
Purity: 95%
Packaging: 1g
Price: $585
Updated: 2021/12/16

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5-FLUOROBENZOFURAN Chemical Properties,Usage,Production

Uses

5-Fluorobenzofuran is an N-Aryloxyethylindolylalkylamine class molecule with dual 5-HT1A and serotonin transporter affinity.

Synthesis

59769-37-8

24410-59-1

General procedure: 1-(2,2-diethoxyethoxy)-4-fluorobenzene (1 mmol), Sn-b catalyst (0.1 g), and trifluorotoluene (10 mL) were added to a 25 mL round bottom flask. The reaction mixture was stirred under reflux conditions and the reaction progress was monitored by gas chromatography (GC). Upon completion of the reaction, the mixture was cooled to room temperature and the Sn-b catalyst was removed by filtration. The filtrate was washed with trifluorotoluene (3 x 10 mL). All filtrates were combined and concentrated under vacuum. Finally, the residue was purified by silica gel (SiO?) column chromatography using petroleum ether/ethyl acetate as eluent to obtain the target product 5-fluorobenzofuran.

References

[1] Tetrahedron, 2015, vol. 71, # 29, p. 4835 - 4841
[2] Journal of Medicinal Chemistry, 2004, vol. 47, # 15, p. 3823 - 3842
[3] Patent: EP1147083, 2004, B1. Location in patent: Page 35
[4] Journal of the American Chemical Society, 2017, vol. 139, # 24, p. 8267 - 8276
[5] European Journal of Organic Chemistry, 2016, vol. 2016, # 13, p. 2268 - 2273

5-FLUOROBENZOFURAN Preparation Products And Raw materials

Raw materials

Preparation Products

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5-FLUOROBENZOFURAN Suppliers

China 65 India 2 United Kingdom 1 United States 10 Global 78

Shanghai Sainty Biotechnology Co., Ltd.

Tel: 021-58957915 17721108391
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J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
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Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
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Hotechem Shanghai Co., Ltd.,

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Tel: 0571-82896630 18969958410
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View Lastest Price from 5-FLUOROBENZOFURAN manufacturers

Career Henan Chemical Co

Product: 5-FLUOROBENZOFURAN 24410-59-1
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: JD 813
Release date: 2019-09-02

24410-59-1, 5-FLUOROBENZOFURANRelated Search:

methyl 5-fluorobenzofuran-2-carboxylate 5-FLUOROBENZO[B]THIOPHENE 5-FLUOROBENZOTHIAZOLE 5-FLUORO-1-BENZOFURAN-2-CARBOXYLIC ACID ETHYL 2-METHYL-4,5,6,7-TETRAFLUOROBENZOFURAN-3-CARBOXYLATE 5-FLUOROBENZOFURAN 5-FLUORO-3-METHYL-1-BENZOFURAN-2-CARBOXYLIC ACID 5-FLUORO-7-HYDROXYBENZOFURAN ETHYL 2-[(TERT-BUTYLTHIO)METHYL]-4,5,6,7-TETRAFLUOROBENZO[B]FURAN-3-CARBOXYLATE 1-[(4,5,6,7-TETRAFLUOROBENZO[B]FURAN-2-YL)METHYL]PYRROLIDINE 2,4-DICHLOROPHENYL 4,5,6,7-TETRAFLUORO-2-METHYLBENZO[B]FURAN-3-CARBOXYLATE 2-([(4,5,6,7-TETRAFLUORO-1-BENZOFURAN-2-YL)METHYL]THIO)PYRIDINIUM-1-OLATE 2-([(2,4-DICHLOROPHENYL)THIO]METHYL)-4,5,6,7-TETRAFLUOROBENZO[B]FURAN N3-(3-CHLORO-4-FLUOROPHENYL)-4,5,6,7-TETRAFLUORO-2-METHYLBENZO[B]FURAN-3-CARBOXAMIDE 2-(([3-(ETHOXYCARBONYL)-4,5,6,7-TETRAFLUOROBENZO[B]FURAN-2-YL]METHYL)THIO)PYRIDINIUM-1-OLATE 2,4-DICHLOROPHENYL 4,5,6,7-TETRAFLUORO-2-METHYLBENZO[B]FURAN-3-SULFONATE 5-Fluoro-N,N,3-trimethyl-2-benzofurancarboxamide 4,5,6,7-TETRAFLUORO-2-METHYL-1-BENZOFURAN-3-CARBOXYLIC ACID

5-FLUOROBENZOFURAN

5-fluoro-1-benzofuran

Benzofuran, 5-fluoro-

5-Fluoro[b]benzofuran

5-Fluorobenzo[b]furan

5-Fluorobenzo[b]furan 95+%

24410-59-1

C8H5FO