ChemicalBook > CAS DataBase List > DIPPA HYDROCHLORIDE
DIPPA HYDROCHLORIDE
- Product Name
- DIPPA HYDROCHLORIDE
- CAS No.
- 155512-52-0
- Chemical Name
- DIPPA HYDROCHLORIDE
- Synonyms
- DIPPA HYDROCHLORIDE;(S)-DIPPA HYDROCHLORIDE;(S)-DIPPA hydrochloride in methanol;2-(3,4-DICHLOROPHENYL)-N-METHYL-N-[(1S)-(3-ISOTHIOCYANATOPHENYL)-2-(1-PYRROLIDINYL)ETHYL]ACETAMIDE HYDROCHLORIDE;2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl]acetamidehydrochloride;2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl]acetamide hydrochloride;2-(3,4-DICHLOROPHENYL)-N-METHYL-N-[(1S)-1-(3-ISOTHIOCYANATOPHENYL)-2-(1-PYRROLIDINYL)ETHYL]ACETAMIDE HYDROCHLORIDE
- CBNumber
- CB1449770
- Molecular Formula
- C22H24Cl3N3OS
- Formula Weight
- 484.86
- MOL File
- Mol file
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DIPPA HYDROCHLORIDE Property
- storage temp.
- 2-8°C
- solubility
- DMSO: 26 mg/mL
- form
- solid
- color
- off-white
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N-Bromosuccinimide Price
Tocris
- Product number
- 0794
- Product name
- DIPPAhydrochloride
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $170
- Updated
- 2021/12/16
Tocris
- Product number
- 0794
- Product name
- DIPPAhydrochloride
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $710
- Updated
- 2021/12/16
Usbiological
- Product number
- 255154
- Product name
- DIPPA hydrochloride
- Packaging
- 10mg
- Price
- $418
- Updated
- 2021/12/16
TRC
- Product number
- D492350
- Product name
- DIPPAHydrochloride
- Packaging
- 100mg
- Price
- $1210
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B6456
- Product name
- DIPPAhydrochloride
- Packaging
- 10mg
- Price
- $251
- Updated
- 2021/12/16
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DIPPA HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
DIPPA Hydrochloride acts as a selective antagonist to the κ-opioid receptor with a significant effect in vivo. Potential anti-depressant. Antagonist.
in vivo
DIPPA (2.5 and 5 mg/kg; s.c.) hydrochloride decreases the latency to feed in Wistar Kyoto rats, but treatment did not alter approach latencies in SD rats[2].
DIPPA (1 and 5 mg/kg; s.c.) hydrochloride high dose increases immobility in SD rats compared to the saline-treated strain control group[2].
DIPPA (5 mg/kg) hydrochloride decreases consumption in SD rats compared to the 5 mg/kg group of Wistar Kyoto rats. DIPPA hydrochloride significantly decreases burying time in both strains. DIPPA (5 mg/kg) hydrochloride decreases burying in both strains compared to the within strain control groups. DIPPA hydrochloride tends to decrease consumption in SD rats in the home cage but significantly increases feeding in the novel cage where potential anxiolytic-like effects of DIPPA hydrochloride may oppose the hypophagic effects of the compound[2].
| Animal Model: | Wistar Kyoto rats and SD rats (250–300 g)[2] |
| Dosage: | 2.5 and 5 mg/kg |
| Administration: | S.c. |
| Result: | Decreased the latency to feed in Wistar Kyoto rats, but treatment did not alter approach latencies in SD rats. |
| Animal Model: | Wistar Kyoto rats and SD rats (250–300 g)[2] |
| Dosage: | 1 and 5 mg/kg |
| Administration: | S.c. |
| Result: | High dose increased immobility in SD rats compared to the saline-treated strain control group. |
IC 50
κ Opioid Receptor/KOR
storage
Desiccate at -20°C
DIPPA HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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