DODECANOIC ACID-1-13C

DODECANOIC ACID-1-13C Property

Melting point:

44-46 °C(lit.)

Boiling point:

225 °C100 mm Hg(lit.)

Flash point:

>230 °F

storage temp. 

Store at -20°C

solubility 

DMF: 30 mg/ml,DMSO: 20 mg/ml,Ethanol: 30 mg/ml

form 

A crystalline solid

color 

White to off-white

CAS Number Unlabeled

143-07-7

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/39

WGK Germany 

3

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

DODECANOIC ACID-1-13C Chemical Properties,Usage,Production

Description

Lauric acid-¹³C is intended for use as an internal standard for the quantification of lauric acid by GC- or LC-MS. Lauric acid is a medium-chain saturated fatty acid. It has been found at high levels in coconut oil. Lauric acid induces the activation of NF-κB and the expression of COX-2, inducible nitric oxide synthase (iNOS), and IL-1α in RAW 264.7 cells when used at a concentration of 25 μM.

Uses

Lauric acid-13C is the 13C labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.

References

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110