AMAROGENTIN

ChemicalBook > CAS DataBase List > AMAROGENTIN

Product Name: AMAROGENTIN
CAS No.: 21018-84-8
Chemical Name: AMAROGENTIN
Synonyms: AMAROGENTIN;Amarogentin-RM;Amarogentin Hydrate;Amarogentin from Gentia lutea;Amarogentin, 98%, from Gentiana scabra Bunge;(4aS)-6α-[2-O-[(3,3',5-Trihydroxy-1,1'-biphenyl-2-yl)carbonyl]-β-D-glucopyranosyloxy]-5β-vinyl-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-1-one;1H,3H-Pyrano[3,4-c]pyran-1-one, 5-ethenyl-4,4a,5,6-tetrahydro-6-[[2-O-[(3,3',5-trihydroxy[1,1'-biphenyl]-2-yl)carbonyl]-β-D-glucopyranosyl]oxy]-, (4aS,5R,6S)-;(2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-2-(((3S,4R,4aS)-8-oxo-4-vinyl-3,4,4a,5,6,8-hexahydropyrano[3,4-c]pyran-3-yl)oxy)tetrahydro-2H-pyran-3-yl 3,3',5-trihydroxy-[1,1'-biphenyl]-2-carboxylate;(2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-2-(((3S,4R,4aS)-8-oxo-4-vinyl-3,4,4a,5,6,8-hexahydropyrano[3,4-c]pyran-3-yl)oxy)tetrahydro-2H-pyran-3-yl 3,3',5-trihydroxy-[1,1'-biphenyl]-2-carboxylate
CBNumber: CB1452325
Molecular Formula: C29H30O13
Formula Weight: 586.54
MOL File: 21018-84-8.mol

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AMAROGENTIN Property

Melting point:: 229-230° (monohydrate)
alpha: D20 -116.6° (methanol)
Boiling point:: 928.5±65.0 °C(Predicted)
Density: 1.59±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMF: 1 mg/ml; DMSO: 2 mg/ml; PBS (pH 7.2): 0.1 mg/ml
form: A crystalline solid
pka: 7.42±0.40(Predicted)
color: White to off-white
LogP: 2.503 (est)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 24914
Product name: Amarogentin
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 24914
Product name: Amarogentin
Purity: ≥98%
Packaging: 5mg
Price: $116
Updated: 2024/03/01

Cayman Chemical

Product number: 24914
Product name: Amarogentin
Purity: ≥98%
Packaging: 10mg
Price: $184
Updated: 2024/03/01

Cayman Chemical

Product number: 24914
Product name: Amarogentin
Purity: ≥98%
Packaging: 25mg
Price: $381
Updated: 2024/03/01

Usbiological

Product number: 361755
Product name: Amarogentin
Packaging: 10mg
Price: $439
Updated: 2021/12/16

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AMAROGENTIN Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the dry roots and rhizomes of Gentiana Gentiana scabra Bge.

Uses

Amarogentin has the functions of protecting liver and gallbladder, inhibiting bacteria and diuretic.

Definition

ChEBI: Amarogentin is a secoiridoid glycoside that consists of (4aS,5R,6R)-5-ethenyl-6-hydroxy-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-1-one having a 2-O-[(3,3',5-trihydroxybiphenyl-2-yl)carbonyl]-beta-D-glucopyranosyl group attached at position 6 via a glycosidic linkage. It has a role as an EC 5.99.1.2 (DNA topoisomerase) inhibitor and a metabolite. It is a secoiridoid glycoside and a monosaccharide derivative.

target

Target	Value
TAS2R1 ()
TNF-α ()
AMPK ()

AMAROGENTIN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from AMAROGENTIN manufacturers

Henan Bao Enluo International TradeCo.，LTD

Product: Amarogentin 21018-84-8
Price: US $100.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500t/month
Release date: 2023-06-15

Career Henan Chemical Co

Product: Amarogentin 21018-84-8
Price: US $2.00/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 20 tons
Release date: 2019-12-26

21018-84-8, AMAROGENTINRelated Search:

Valtrate 1α-(β-D-Glucopyranosyloxy)-1,4a,5,6,7,7aα-hexahydro-4aα-hydroxy-7α-methyl-5-oxocyclopenta[c]pyran-4-carboxylic acid methyl ester Amygdalin 4-Biphenylcarboxylic acid 3-Hydroxy-4-methylbenzoic acid METHYL 3-HYDROXY-4-METHYLBENZOATE 3,5-Dihydroxy-4-methylbenzoic acid Methyl 4-phenylbenzoate AMAROGENTIN BIPHENYL-3-CARBOXYLIC ACID ETHYL ESTER METHYL 3,5-DIHYDROXY-4-METHYLBENZOATE 3'-HYDROXYBIPHENYL-4-CARBOXYLIC ACID METHYL ESTER METHYL 5,5-DIMETHOXYVALERATE BENZYL BETA-D-GLUCOPYRANOSIDE AMAROGENTIN(P) Amarogentin hexaacetate BETA-ISOBUTOXYACROLEIN 2-Ethoxy-3,4-dihydro-4-methyl-2H-pyran

(4aS)-6α-[2-O-[(3,3',5-Trihydroxy-1,1'-biphenyl-2-yl)carbonyl]-β-D-glucopyranosyloxy]-5β-vinyl-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-1-one

Amarogentin from Gentia lutea

Amarogentin, 98%, from Gentiana scabra Bunge

Amarogentin Hydrate

AMAROGENTIN

1H,3H-Pyrano[3,4-c]pyran-1-one, 5-ethenyl-4,4a,5,6-tetrahydro-6-[[2-O-[(3,3',5-trihydroxy[1,1'-biphenyl]-2-yl)carbonyl]-β-D-glucopyranosyl]oxy]-, (4aS,5R,6S)-

(2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-2-(((3S,4R,4aS)-8-oxo-4-vinyl-3,4,4a,5,6,8-hexahydropyrano[3,4-c]pyran-3-yl)oxy)tetrahydro-2H-pyran-3-yl 3,3',5-trihydroxy-[1,1'-biphenyl]-2-carboxylate

Amarogentin-RM

21018-84-8

21018-84-6

C27H28O14

C29H30O13