ChemicalBook > CAS DataBase List > AYANIN
AYANIN
- Product Name
- AYANIN
- CAS No.
- 572-32-7
- Chemical Name
- AYANIN
- Synonyms
- AYANIN;Ayarin;NSC 691652;3,7,4'-Tri-O-methylquercetin;Quercetin 3,4',7-trimethyl ether;QUERCETIN 3,7,4'-TRIMETHYL ETHER;5,3'-Dihydroxy-3,7,4'-trimethoxyflavone;3',5-Dihydroxy-3,4',7-trimethoxyflavone;5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxychromen-4-one;2-(3-Hydroxy-4-methoxyphenyl)-3,7-dimethoxy-5-hydroxy-4H-1-benzopyran-4-one
- CBNumber
- CB1455573
- Molecular Formula
- C18H16O7
- Formula Weight
- 344.32
- MOL File
- 572-32-7.mol
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AYANIN Property
- Melting point:
- 173℃
- Boiling point:
- 600.8±55.0 °C(Predicted)
- Density
- 1.45±0.1 g/cm3(Predicted)
- storage temp.
- 4°C, protect from light
- form
- Solid
- pka
- 6.15±0.40(Predicted)
- color
- White to yellow
- InChI
- InChI=1S/C18H16O7/c1-22-10-7-12(20)15-14(8-10)25-17(18(24-3)16(15)21)9-4-5-13(23-2)11(19)6-9/h4-8,19-20H,1-3H3
- InChIKey
- KPCRYSMUMBNTCK-UHFFFAOYSA-N
- SMILES
- C1(C2=CC=C(OC)C(O)=C2)OC2=CC(OC)=CC(O)=C2C(=O)C=1OC
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0023515
- Product name
- Ayanin
- Packaging
- 1mg
- Price
- $200
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0023515
- Product name
- Ayanin
- Packaging
- 5mg
- Price
- $500
- Updated
- 2021/12/16
Arctom
- Product number
- AS143007
- Product name
- Ayanin
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $282
- Updated
- 2021/12/16
Arctom
- Product number
- CFN96157
- Product name
- Ayanin
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $288
- Updated
- 2021/12/16
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AYANIN Chemical Properties,Usage,Production
Uses
Ayanin is a bioflavonoid isolated from Croton schiedeanus Schlecht. Ayanin is a non-selective phosphodiesterase inhibitor.
Definition
ChEBI: 3',5-dihydroxy-3,4',7-trimethoxyflavone is a trimethoxyflavone that is quercetin in which the hydroxy groups at positions 3, 4' and 7 have been replaced by methoxy groups. It has a role as a plant metabolite. It is a dihydroxyflavone and a trimethoxyflavone. It is functionally related to a quercetin. It is a conjugate acid of a 3',5-dihydroxy-3,4',7-trimethoxyflavone(1-).
Biological Activity
Ayanin is a biologically active flavonoid isolated from Croton schiedeanus Schlecht. Ayanin is a non-selective phosphodiesterase (phosphodiesterase1-4) inhibitor, which can be used in the study of respiratory diseases, such as allergic asthma.
in vitro
Ayanin inhibits interleukin (IL)-4 production from purified basophils with an IC 50 value of 2.2 μM.
target
| PDE2A
| PDE4
|