ChemicalBook > CAS DataBase List > 5-[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]-5-oxopentanoic acid
5-[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]-5-oxopentanoic acid
- Product Name
- 5-[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]-5-oxopentanoic acid
- CAS No.
- 959053-53-3
- Chemical Name
- 5-[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]-5-oxopentanoic acid
- Synonyms
- N-Boc-piperazine-C3-COOH;1-Piperazinepentanoic acid, 4-[(1,1-dimethylethoxy)carbonyl]-δ-oxo-;5-[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]-5-oxopentanoic acid
- CBNumber
- CB14574647
- Molecular Formula
- C14H24N2O5
- Formula Weight
- 300.35
- MOL File
- 959053-53-3.mol
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5-[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]-5-oxopentanoic acid Chemical Properties,Usage,Production
Biological Activity
N-Boc-piperazine-C3-COOH is a PROTAC linker, which refers to the alkyl/ether composition. Boc-N-piperazine-C3-COOH can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 [1].
References
[1]. Cheng B, Ren Y, Cao H, Chen J. Discovery of novel resorcinol diphenyl ether-based PROTAC-like molecules as dual inhibitors and degraders of PD-L1. Eur J Med Chem. 2020;199:112377.
5-[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]-5-oxopentanoic acid Preparation Products And Raw materials
Raw materials
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