ChemicalBook > CAS DataBase List > 4,6,7,8-TETRAHYDRO-1H,3H-QUINOLINE-2,5-DIONE

4,6,7,8-TETRAHYDRO-1H,3H-QUINOLINE-2,5-DIONE

Product Name: 4,6,7,8-TETRAHYDRO-1H,3H-QUINOLINE-2,5-DIONE
CAS No.: 5057-12-5
Chemical Name: 4,6,7,8-TETRAHYDRO-1H,3H-QUINOLINE-2,5-DIONE
Synonyms: NSC 160504;Carteolol Impurity 1;Carteolol EP Impurity A;Cartenolol EP Impurity A;Carteolol Hydrochloride impurity A;Carteolol hydrochloride EP Impurity A;3,4,7,8-Tetrahydroquinoline-2,5(1H,6H);1,3,4,6,7,8-hexahydroquinoline-2,5-quinone;4,6,7,8-tetrahydroquinoline-2,5(1H,3H)-dione;1,2,3,4,5,6,7,8-octahydroquinoline-2,5-dione
CBNumber: CB1458332
Molecular Formula: C9H11NO2
Formula Weight: 165.19
MOL File: 5057-12-5.mol

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4,6,7,8-TETRAHYDRO-1H,3H-QUINOLINE-2,5-DIONE Property

Melting point:: 196-198°C
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: Pale Beige to Beige

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Safety

Hazard Codes: Xi
HazardClass: IRRITANT
HS Code: 2933499090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: T293845
Product name: 4,6,7,8-Tetrahydro-2,5(1H,3H)-quinolinedione
Packaging: 50mg
Price: $315
Updated: 2021/12/16

TRC

Product number: T293845
Product name: 4,6,7,8-Tetrahydro-2,5(1H,3H)-quinolinedione
Packaging: 100mg
Price: $605
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0024992
Product name: 4,6,7,8-TETRAHYDRO-1H,3H-QUINOLINE-2,5-DIONE
Purity: 95.00%
Packaging: 1G
Price: $722.8
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0024992
Product name: 4,6,7,8-TETRAHYDRO-1H,3H-QUINOLINE-2,5-DIONE
Purity: 95.00%
Packaging: 5G
Price: $1115.96
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0024992
Product name: 4,6,7,8-TETRAHYDRO-1H,3H-QUINOLINE-2,5-DIONE
Purity: 95.00%
Packaging: 10G
Price: $1585.35
Updated: 2021/12/16

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4,6,7,8-TETRAHYDRO-1H,3H-QUINOLINE-2,5-DIONE Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

4,6,7,8-Tetrahydro-2,5(1H,3H)-quinolinedione (cas# 5057-12-5) is a compound useful in organic synthesis.

Synthesis

504-02-9

79-10-7

5057-12-5

General method: 1,3-Cyclohexanedione (8.9 mmol, 1 eq.) was mixed with acrylic acid (10.6 mmol, 1.2 eq.) in a reaction vial. Ammonium acetate (10.6 mmol, 1.2 eq.) was then added. The reaction mixture was thoroughly mixed using a spatula and heated with stirring at 80 °C for 5 h under nitrogen protection. After completion of the reaction, it was cooled to room temperature and the reaction mixture was diluted with 10 mL of distilled water followed by two extractions with ethyl acetate (2 × 10 mL). The organic extracts were combined and dried with anhydrous Na2SO4. After filtration, the solvent was removed by evaporation under reduced pressure and the resulting crude product was purified by column chromatography (eluent: ethyl acetate/hexane) to afford the target compound 3,4,7,8-tetrahydroquinoline-2,5(1H,6H)-dione. Characterization data of the compounds are provided.

References

[1] Synthetic Communications, 2013, vol. 43, # 22, p. 3010 - 3019

4,6,7,8-TETRAHYDRO-1H,3H-QUINOLINE-2,5-DIONE Preparation Products And Raw materials

Raw materials

Preparation Products

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4,6,7,8-TETRAHYDRO-1H,3H-QUINOLINE-2,5-DIONE Suppliers

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5057-12-5, 4,6,7,8-TETRAHYDRO-1H,3H-QUINOLINE-2,5-DIONERelated Search:

3,4,5,6,7,8-HEXAHYDRO-2(1H)-QUINOLINONE 4,6,7,8-TETRAHYDRO-1H,3H-QUINOLINE-2,5-DIONE 4-(2,5-DIOXO-4-PHENYL-3,4,5,6,7,8-HEXAHYDRO-2H-QUINOLIN-1-YL)-BENZOIC ACID

Carteolol EP Impurity A

3,4,7,8-Tetrahydroquinoline-2,5(1H,6H)

4,6,7,8-TETRAHYDRO-1H,3H-QUINOLINE-2,5-DIONE

4,6,7,8-TETRAHYDRO-2,5(1H,3H)-QUINOLINEDIONE

2,5-Dioxo-1,2,3,4,5,6,7,8-octahydroquinoline

3,4,7,8-Tetrahydroquinoline-2,5(1H,6H)-dione

4,6,7,8-Tetrahydro-3,4,5,6,7,8-hexahydrocarbostyril-5-one

NSC 160504

Carteolol Hydrochloride impurity A

1,2,3,4,5,6,7,8-octahydroquinoline-2,5-dione

4,6,7,8-tetrahydroquinoline-2,5(1H,3H)-dione

1,3,4,6,7,8-hexahydroquinoline-2,5-quinone

1,3,4,6,7,8-hexahydroquinoline-2,5-dione(For export only)

Carteolol Impurity 1

Carteolol hydrochloride EP Impurity A

Cartenolol EP Impurity A

5057-12-5

Heterocycles