Palmitoyl-L-Carnitine Chloride
- Product Name
- Palmitoyl-L-Carnitine Chloride
- CAS No.
- 18877-64-0
- Chemical Name
- Palmitoyl-L-Carnitine Chloride
- Synonyms
- Einecs 242-642-6;L-CARNITINE:HCL, O-PALMITOYL;L-Palmitoylcarnitine chloride;PALMITOYL-L-CARNITINE CHLORIDE;O-PALMITOYL-L-CARNITINE CHLORIDE;HEXADECANOYL-L-CARNITINE CHLORIDE;Palmitoyl-L-carnitine hydrochloride;Palmitoyl-
L -carnitine chloride;Palmitoyl-L-carnitine chloride≥ 99% (TLC);Palmitoyl-L-carnitine chloride in Methanol - CBNumber
- CB1462919
- Molecular Formula
- C23H46ClNO4
- Formula Weight
- 436.07
- MOL File
- 18877-64-0.mol
Palmitoyl-L-Carnitine Chloride Property
- Melting point:
- 168-172 °C(lit.)
- storage temp.
- -20°C
- solubility
- H2O: 25 mg/mL with heat or sonication
- form
- powder
- color
- white
- Appearance
- white solid
- Water Solubility
- H2O: 25mg/mL (with he at or sonication)
- BRN
- 4071005
- InChI
- InChI=1/C23H45NO4.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(27)28-21(19-22(25)26)20-24(2,3)4;/h21H,5-20H2,1-4H3;1H/t21-;/s3
- InChIKey
- GAMKNLFIHBMGQT-GKNLIIIVNA-N
- SMILES
- [C@@H](CC(=O)O)(C[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCC.[Cl-] |&1:0,r|
- CAS DataBase Reference
- 18877-64-0
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P1645
- Product name
- Palmitoyl-L-carnitine chloride
- Purity
- ≥98% (TLC), powder
- Packaging
- 5mg
- Price
- $139
- Updated
- 2025/07/31
- Product number
- P1645
- Product name
- Palmitoyl-L-carnitine chloride
- Purity
- ≥98% (TLC), powder
- Packaging
- 10mg
- Price
- $292
- Updated
- 2025/07/31
- Product number
- P2548
- Product name
- Palmitoyl-L-carnitine Hydrochloride
- Purity
- >98.0%(HPLC)
- Packaging
- 25mg
- Price
- $358
- Updated
- 2025/07/31
- Product number
- 26553
- Product name
- Palmitoyl-L-carnitine (chloride)
- Packaging
- 5mg
- Price
- $117
- Updated
- 2024/03/01
- Product number
- 26553
- Product name
- Palmitoyl-L-carnitine (chloride)
- Packaging
- 50mg
- Price
- $636
- Updated
- 2024/03/01
Palmitoyl-L-Carnitine Chloride Chemical Properties,Usage,Production
Description
Hexadecanoylcarnitine, also called as palmitoyl-L-carnitine, is an endogenous acylcarnitine and acts as a key energy donor for β-oxidation. Hexanoylcarnitine chloride is used as an analytical standard in HPLC-MS and MS/MS studies.
Hexanoylcarnitine has surface activity, has a diphilic character and has detergent properties. Hexanoylcarnitine has surface activity, is diphilic and has detergent properties. Hexanoylcarnitine promotes the transfer of long-chain fatty acids from cytoplasm to mitochondria during fatty acid oxidation. The substance accumulates in the myocardium during ischemia and affects the levels of phosphate and free fatty acids in the myocardium and on the myocardial vascular endothelium. In experimental models, palmitoyl-L-carnitine levels increased with age and induced mitochondrial dysfunction in neurons.
Palmitoyl-L-carnitine may be used as an analytical standard to quantify the analyte in biological samples of patients with continuous ambulatory peritoneal dialysis (CAPD) or automated peritoneal dialysis (APD) using HPLC-MS. It may also be used as an analytical reference standard for the separation and identification of underivatized palmitoyl-L-carnitine in human plasma samples.
The product is used primarily as a control for MS/MS.
Chemical Properties
White crystalline powder
Uses
Palmitoyl-L-carnitine Hydrochloride is a long-chain fatty ester of carnitine which is accumulated and released into the circulation, in fatty-acid oxidation defects. Pattern of Lauroyl-L-carnitine can be diagnostic for a number of ?-oxidation defects.
Uses
Palmitoyl-L-carnitine chloride has been used as acylcarnitine in treating cardiomyocytes for the induction of reactive oxygen species (ROS).
Biochem/physiol Actions
Long-chain acylcarnitine and well-known intermediate in mitochondrial fatty acid oxidation. Modifies myocardial levels of high-energy phosphates and free fatty acids in the heart. Increases erythroid colony formation in culture. Reduces surface negative charge of erythrocytes and myocytes. Reported to affect currents and inhibit endothelium-dependent relaxation induced by acetylcholine and substance P in a dose-dependent manner by suppressing the intracellular calcium signal transduction in endothelial cells. Inhibits the Na/K pump current but has no effect on the intracellular calcium current in guinea pig ventricular cells. However, like oubain, it reversibly depolarizes the resting membrane, decreases action potential duration, and increases the amplitude of myocyte contractions.
IC 50
Kir6.2; Human Endogenous Metabolite
Palmitoyl-L-Carnitine Chloride Preparation Products And Raw materials
Raw materials
Preparation Products
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