ChemicalBook > CAS DataBase List > BI8626

BI8626

Product Name
BI8626
CAS No.
1875036-75-1
Chemical Name
BI8626
Synonyms
T14569;BI8626;BI8626 (BI-8626;BI8626, 10 mM in DMSO;N-[3-(Aminomethyl)benzyl]-8-(4-benzyl-1-piperazinyl)pyrimido[5,4-d]pyrimidin-4-amine;N-(3-(Aminomethyl)benzyl)-8-(4-benzylpiperazin-1-yl)pyrimido[5,4-d]pyrimidin-4-amine;1,3-Benzenedimethanamine, N1-[8-[4-(phenylmethyl)-1-piperazinyl]pyrimido[5,4-d]pyrimidin-4-yl]-
CBNumber
CB14667639
Molecular Formula
C25H28N8
Formula Weight
440.56
MOL File
1875036-75-1.mol
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BI8626 Property

Boiling point:
654.4±55.0 °C(Predicted)
Density 
1.302±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : 83.33 mg/mL (189.15 mM; Need ultrasonic)
form 
Solid
pka
9.01±0.10(Predicted)
color 
Light yellow to yellow
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Safety

WGK Germany 
WGK 3
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML3149
Product name
BI8626
Purity
≥98% (HPLC)
Packaging
5MG
Price
$123
Updated
2026/04/30
Sigma-Aldrich
Product number
SML3149
Product name
BI8626
Purity
≥98% (HPLC)
Packaging
25MG
Price
$396
Updated
2026/04/30
ChemScene
Product number
CS-0077135
Product name
BI8626
Purity
98.49%
Packaging
5mg
Price
$350
Updated
2021/12/16
ChemScene
Product number
CS-0077135
Product name
BI8626
Purity
98.49%
Packaging
10mg
Price
$650
Updated
2021/12/16
ChemScene
Product number
CS-0077135
Product name
BI8626
Purity
98.49%
Packaging
50mg
Price
$2000
Updated
2021/12/16
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BI8626 Chemical Properties,Usage,Production

Uses

BI8626 is a specific inhibitor of the ubiquitin ligase HUWE1 with an IC50 of 0.9 μM[1].

Biological Activity

BI8626 is a specific antagonist of the ubiquitin ligase HUWE1 with IC50 of 0.9 μM.

target

IC50: 0.9 μM (HUWE1)

References

[1] Peter S, et al. Tumor cell-specific inhibition of MYC function using small molecule inhibitors of the HUWE1 ubiquitin ligase.EMBO Mol Med. 2014 Dec;6(12):1525-41. DOI:10.15252/emmm.201403927

BI8626 Preparation Products And Raw materials

Raw materials

Preparation Products

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BI8626 Suppliers

China 30 India 1 United States 4 Global 35
Shanghai Haozhixiang Biotechnology Co., Ltd
Tel
526763801 13301653310
Fax
+86-21-51619052
Email
526763801@qq.com
Country
China
ProdList
9445
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
89689
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32467
Advantage
58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel
86-571-88216897,88216896 13588875226
Fax
86-571-88216895
Email
sales@hzclap.com
Country
CHINA
ProdList
6312
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
ShangHai ChuanQian Chemcial Technique Centre
Tel
15869524721
Email
3525679403@qq.com
Country
China
ProdList
4410
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24960
Advantage
58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
Tel
024-024-024-88590548 18341751992
Email
757984502@qq.com
Country
China
ProdList
962
Advantage
58

1875036-75-1, BI8626Related Search:


  • BI8626 (BI-8626
  • BI8626
  • 1,3-Benzenedimethanamine, N1-[8-[4-(phenylmethyl)-1-piperazinyl]pyrimido[5,4-d]pyrimidin-4-yl]-
  • N-(3-(Aminomethyl)benzyl)-8-(4-benzylpiperazin-1-yl)pyrimido[5,4-d]pyrimidin-4-amine
  • N-[3-(Aminomethyl)benzyl]-8-(4-benzyl-1-piperazinyl)pyrimido[5,4-d]pyrimidin-4-amine
  • BI8626, 10 mM in DMSO
  • T14569
  • 1875036-75-1
  • C25H28N8