2'-O-(2-Cyanoethyl)adenosine

Product Name: 2'-O-(2-Cyanoethyl)adenosine
CAS No.: 2226475-42-7
Chemical Name: 2'-O-(2-Cyanoethyl)adenosine
Synonyms: 2'-O-(2-Azidoethyl)adenosine;2'-O-(2-Cyanoethyl)adenosine
CBNumber: CB14672415
Molecular Formula: C12H16N8O4
Formula Weight: 336.31
MOL File: 2226475-42-7.mol

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2'-O-(2-Cyanoethyl)adenosine Chemical Properties,Usage,Production

Uses

2’-O-(2-Azidoethyl)adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 2’-O-(2-Azidoethyl)adenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

2'-O-(2-Cyanoethyl)adenosine Preparation Products And Raw materials

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2226475-42-7, 2'-O-(2-Cyanoethyl)adenosineRelated Search:

2'-O-(2-Cyanoethyl)adenosine

2'-O-(2-Azidoethyl)adenosine

2226475-42-7