(3aS,4S,6aR)-4-(4-aminobutyl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one

(3aS,4S,6aR)-4-(4-aminobutyl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one Property

Boiling point:

478.0±30.0 °C(Predicted)

Density 

1.162±0.06 g/cm3(Predicted)

storage temp. 

4°C, protect from light

solubility 

H2O : 200 mg/mL (928.85 mM; ultrasonic and warming and heat to 60°C)

form 

Solid

pka

13.90±0.40(Predicted)

color 

White to off-white

Hazard and Precautionary Statements (GHS)

(3aS,4S,6aR)-4-(4-aminobutyl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one Chemical Properties,Usage,Production

Uses

Norbiotinamine is an alternative to biotin. Norbiotinamine can be coupled with a carboxylic group of amino acids to give inverse peptides, having the amide linkage oriented in the opposite direction[1].

References

[1] Szalecki W.Synthesis of?Norbiotinamine?and its derivatives. Bioconjug Chem.?1996 Mar-Apr;7(2):271-3. DOI:10.1021/bc950094f
[2] Zhou GC,?et al. Design, synthesis and evaluation of a cellular stable and detectable biotinylated fumagillin probe and investigation of cell permeability of fumagillin and its analogs to endothelial and cancer cells.Eur J Med Chem.?2013;70:631-9. DOI:10.1016/j.ejmech.2013.10.033